Acid-Base balance Flashcards

1
Q

what is the normal pH of the body?

A

tightly controlled around 7.35 and 7.45 pH

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2
Q

what does normal metabolism result in the production of?

A

results in the production of hydrogen ions, causing the normal body metabolism to become ACIDIC

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3
Q

if the body’s metabolism is becoming more acidic, what 2 things help body avoid a decrease in pH?

A

1) increase the BUFFERING of acids

2) excreting acids

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4
Q

why is bicarbonate as a buffer so important?

A

Because it NEVER REACHES EQUILIBRIUM, therefore, it prevents the increase of metabolic acids.

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5
Q

if it involves pCO2, is the component respiratory or metabolic?

A

RESPIRATORY

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6
Q

if it involves HCO3-, is the component respiratory or metabolic?

A

METABOLIC

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7
Q

what does acidosis refers to?

A

an INCREASE in H+

or

a process tending to cause an increase in H+

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8
Q

what does alkalosis refer to?

A

a DECREASE IN H+

or

a process tending to cause a decrease in H+

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9
Q

what is acidaemia?

A

increase in H+

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10
Q

what is alkalaemia?

A

decrease in H+

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11
Q

what does respiratory acidosis mean?

A

pH low
Due to;
- normal HCO3
- PCO2 high

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12
Q

what does metabolic acidosis mean?

A

pH low
Due to;
- normal PCO2
- low HCO3

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13
Q

what does respiratory alkalosis mean?

A

pH high
Due to;
- normal HCO3
- low PCO2

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14
Q

what does metabolic alkalosis mean?

A

pH high
Due to;
- normal PCO2
- high HCO3

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15
Q

H+ + HCO3- ARROW H2CO3 ARROW CO2 + H20

What happens if theres too much H+?

A
  • too much H+
  • all the buffer, HCO3, is used up trying to reduce the levels of H+
  • causes HCO3- levels to decrease

= metabolic acidosis

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16
Q

H+ + HCO3- ARROW H2CO3 ARROW CO2 + H20

What happens if theres too much CO2?

A
  • too much CO2
  • lungs are unable to blow off CO2 in the normal way
  • increase in H+

= respiratory acidosis

17
Q

H+ + HCO3- ARROW H2CO3 ARROW CO2 + H20

What happens if theres too little H+?

A
  • too little H+
  • HCO3- levels increase to compensate

= metabolic alkalosis

18
Q

H+ + HCO3- ARROW H2CO3 ARROW CO2 + H20

What happens if theres too little CO2?

A
  • too little CO2
  • H+ ions decrease

= respiratory alkalosis

19
Q

causes of respiratory acidosis?

A
  • choking
  • bronchopneumonia
  • COAD = chronic obstructive airway disease
20
Q

causes of respiratory alkalosis?

A
  • hysterical over-breathing
  • mechanical over-ventilation
  • raised intracranial pressure
21
Q

causes of metabolic acidosis?

A
  • impaired H+ excretion
  • increased H+ production or ingestion
  • loss of HCO3-
22
Q

causes of metabolic alkalosis?

A
  • loss of H+ in vomit
  • alkali ingestion
  • potassium deficiency
23
Q

how do the kidneys compensate for decreases in pH (i.e. more acidic)?

A
  • they increase the excretion of H+ ions by conserving bicarbonate