Small intestine disorders and investigations Flashcards
Does the small intestine have a high or low bacterial population?
Low
What are some functions of the small intestine?
Decontaminates food
Controls hydrolysis
Barrier against pathogens
What are some investigations for small intestine structure?
Endoscopy/biopsy CT MRI Capsule endoscopy Double balloon entersocopy
What conditions may finger clubbing indicate?
Coeliac’s
Crohn’s
What conditions may scleroderma indicate?
Systemic sclerosis
What conditions may aphthuous ulceration indicate?
Coeliac’s
Crohn’s
What is aphthuous ulceration?
A recurrent round or oval sore or ulcer inside the mouth on an area where the skin is not tightly bound to the underlying bone, such as on the inside of the lips and cheeks or underneath the tongue
What condition should all IBS patients be tested for?
Coeliac’s Disease
Plasma levels of what substance would be raised in CD?
IgA
What is the gold standard confirmatory test for CD?
Distal duodenal biopsy
Villous atrophy
What causes CD?
Sensitivity to gliadin
What are some possible complications of CD?
Small bowel lymphoma
Oesophageal carcinoma
Colon cancer
Small bowel adenocarcinoma
What is giardia lamblia?
Unicellular parasite
Causes giardiasis
Present in contaminated water
How is giardiasis treated?
Metronizadole
What are the effects of Whipple’s disease?
Weight loss
Malabsorption
Abdominal pain
Affects skin, bone, joints, cardiac
