Colorectal cancer Flashcards

1
Q

Which test is used to screen colorectal cancer?

A

qFIT

Quantitative faecal immunochemical test

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2
Q

What are some factors which contribute to anorectal continence?

A
Anatomy
Rectal compliance
Stool consistency
Central control
Anorectal sensation
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3
Q

What are some anatomical factors in anorectal continence?

A

Puborectalis sling
Sphincter complex
Anal cushions

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4
Q

What is the overall 10ys for CRC?

A

59.9%

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5
Q

How may CRC present?

A
Colicky abdominal pain
Rectal bleeding
Change in bowel habits
Weight loss
Tenesmus
Fatigue 
Vomiting
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6
Q

List some useful investigations for CRC?

A

Colonoscopy w/ biopsy
CT colonography
Plain CT
Pre-op MRI in confirmed rectal cancer

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7
Q

What are some considerations for surgical solutions for CRC?

A
Resection
Restore intestinal continuity
Faecal diversion (stoma)
Preservation of function
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8
Q

What are some types of polyp which may be found on CRC colonoscopy?

A

Familial adenomatous polyposis
Giant polyp
Pre-dunculated polyp
Flat polyp

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9
Q

Do a majority of CRC’s develop from an adenomatous polyp?

A

Yes

Almost all of them

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10
Q

What is the aim of screening for CRC?

A

Detect polyp before progression to carcinoma

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11
Q

Which side of the bowel are most tumours found?

A

Left

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12
Q

Where does lymph drain from in the rectum?

A

The fatty envelope called the “mesorectum”

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13
Q

What is bowel/intestinal anastomosis?

A

Surgical procedure performed to establish communication between two formerly distant portions of the intestine. This procedure restores intestinal continuity after removal of a pathological condition affecting the bowel

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14
Q

List some possible complications from CRC surgery?

A

Bleeding
Infection
Anastomotic leak
Stoma problems such as ischaemia, retraction or prolapse

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15
Q

What is a possible consequence of untreated complete bowel obstruction?

A

Ischaemia from pressure

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16
Q

What is Hartmann’s procedure?

A

Sigmoid colectomy without anastomosis

17
Q

What causes 60% of large bowel obstructions?

A

Malignancy

18
Q

What are some benign causes of large bowel obstruction?

A
Stricture
Volvulus
Faecal impaction
Intussception
Pseudo-obstruction
19
Q

What is tenesmus?

A

A continual or recurrent inclination to evacuate the bowels, caused by disorder of the rectum or other illness

20
Q

What is volvulus?

A

A loop of intestine twists around itself and the mesentery that supports it, resulting in a bowel obstruction

21
Q

What is intussception?

A

one segment of intestine “telescopes” inside of another, causing an intestinal obstruction

22
Q

What are some main causes of small bowel obstruction?

A

Adhesions

Hernia