Small group Upper GI Flashcards

1
Q

Burning pain, relief with antacids/PPI, lack of exacerbation with exercise:

?

A

GERD

(possible:

  • hiatal hernia w/ reflux
  • ulcer
  • non GERD esophagitis)
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2
Q

Risk factors for GERD

A

Smoking, Alcohol,
Obesity
Male
>50

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3
Q

How should PPI be used?

A

(Omeprazole)
should be taken 30-60 min prior to eating
- since PPIs only act on actively secreting pumps, meals and mornings maximize are optimal

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4
Q

alcohol and tobacco and high fat foods leads to LES ______

A

LES sphincter relaxation

- cutting back can reduce reflux

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5
Q

Caffeine and coffee consumption may do what to contribute to GERD?

A

Increase Gastric acid production

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6
Q

If pt has GERD and is symptomatic for 10 years, (long time) what test should you run?

A

Esophagogastroduodenoscopy (EGD)

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7
Q

Salmon pink: buzz word for?

A

Barrett Esophagus

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8
Q

Red dots seen on reactive squamous epithelium, think . . .

A

eosinophilic esophagitis

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9
Q

squamous pearls seen on biopsy of mass

- think?

A

Squamous cell carcinoma

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10
Q

risk factor for SCC?

A

same as adeno
- smoking, alcohol

But also

  • caustic injury
  • achalasia
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11
Q

Where is adenocarcinoma seen vs SCC for GI?

A

Adeno: by GEJ
- gastric cardia, GEJ, lower eso

SCC: proximal esophagus (midd-upper 1/3)

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12
Q

What is the presence of melena suggestive of?

A

Source proximal to the ligament of Treitz.
Hb –> broken down to hematin (black)

or

Slow bleeding from small bowel and prox colon –> melena

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13
Q

Most common causes of gastric ulcers?

A

H.Pylori (65% stomach, 85% duodenal)

NSAIDS
Tobacco
Neoplasm

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14
Q

Ways to test for H. pylori infxn

A

serum IgG Ab to H. pylori
- identifies exposure, not active infxn

Stool
- antigen to H.Pylori - best but not avail. everywhere

Breath
Urease containing organisms

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15
Q

Is nuclei arranged around basal end more or less malig?

A

less

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16
Q

Complications of peptic ulcer disease

A

Bleeding
perforation
obstruction from edema/scarring

17
Q

Diseases assoc with H. pylori

A

chronic gastritis
PUD
gastric carcinoma
Gastric MALT lymphoma