2 Path of GB and exo pancreas [4]

Question 1

Risk factors for Bile duct carcinoma

Answer 1

(nearly all are adenocarcinoma - poor prog)

1. choledochal cyst in older adults
2. Primary sclerosing cholangitis
3. Infections (liver flukes)
4. cholelithiasis

Question 2

Sequelae of pancreatitis

Answer 2

pseudocysts
abcesses
Pancreatic insufficiency
secondary diabetes

Question 3

Endocrine neoplasia

Answer 3

functional tumor

• Insulinoma (hypoglycemia, feinting)
• Gastrinoma (peptic ulcer disease, ZE)
• Glucagon secreting

Histology
- well demarcated with ribbon like pattern

Question 4

1 cause of acute pancreatitis

Answer 4

Gallstones

Question 5

1 cause of chronic pancreatitis

Answer 5

Alcohol abuse
(then: long standing ductal obstruction
hereditary forms
Idiopathic)

Question 6

most common pancreatic neoplasia

Answer 6

ductal adenocarcinoma

• 3rd leading cause of cancer death