Small Group: Reproductive Health Cases – Amenorrhea, Menopause, and HRT Flashcards
What disorders should you consider in a patient with amenorrhea?
•If she has had periods before:
- Pregnancy
- Premature ovarian failure
- Autoimmune destruction of the ovaries
- Prolactinoma
- Hypothyroidism
- Obesity-related anovulation
- Virilizing tumors
• If she has never had a period:
- Turner syndrome
- Disorders of sex development
Remember: the main difference between PCOS and obesity anovulation syndrome is _____________.
that PCOS presents with an LH:FSH ratio greater than 2.5
What test can help diagnose premature ovarian failure?
If progesterone does not produce a period
In PCOS, _______________ will produce a period.
progesterone
What is thought to initiate puberty?
Withdrawal of the CNS inhibition of GnRH secretion
In what way does estrogen deficiency affect sleep?
It increases the latency to sleep onset.
Some research suggests that women who take prolonged hormone replacement therapy after menopause are at decreased risk of __________________.
developing Alzheimer’s
In general, hormone therapy should only be offered to ______________ women.
symptomatic
Which progestin seems to confer the most cardiovascular risk?
Medroxy-progesterone
The only FDA-approved non-hormonal therapy for menopause is _______________.
paroxetine