Small Group: Reproductive Health Cases – Amenorrhea, Menopause, and HRT Flashcards

1
Q

What disorders should you consider in a patient with amenorrhea?

A

•If she has had periods before:

  • Pregnancy
  • Premature ovarian failure
  • Autoimmune destruction of the ovaries
  • Prolactinoma
  • Hypothyroidism
  • Obesity-related anovulation
  • Virilizing tumors

• If she has never had a period:

  • Turner syndrome
  • Disorders of sex development
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2
Q

Remember: the main difference between PCOS and obesity anovulation syndrome is _____________.

A

that PCOS presents with an LH:FSH ratio greater than 2.5

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3
Q

What test can help diagnose premature ovarian failure?

A

If progesterone does not produce a period

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4
Q

In PCOS, _______________ will produce a period.

A

progesterone

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5
Q

What is thought to initiate puberty?

A

Withdrawal of the CNS inhibition of GnRH secretion

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6
Q

In what way does estrogen deficiency affect sleep?

A

It increases the latency to sleep onset.

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7
Q

Some research suggests that women who take prolonged hormone replacement therapy after menopause are at decreased risk of __________________.

A

developing Alzheimer’s

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8
Q

In general, hormone therapy should only be offered to ______________ women.

A

symptomatic

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9
Q

Which progestin seems to confer the most cardiovascular risk?

A

Medroxy-progesterone

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10
Q

The only FDA-approved non-hormonal therapy for menopause is _______________.

A

paroxetine

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