skin terms exam 3 Flashcards

1
Q

what is the hallmark skin lesion of hyperadrenocorticism

A

calcinosis cutis

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2
Q

name the four layers of the epidermis

A

stratum corneum, s. granulosum, s. spinosum, s. basale

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3
Q

what two layers of epidermis does Pemphigus foliaceus target

A

s. granulosum and s. spinosum

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4
Q

what is cornification

A

active process of s. basale reproducing and turning over epidermis.

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5
Q

what is the role of desmosomes

A

bridges between all the keratinocytes help resist shearing forces.

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6
Q

what creates sebum

A

holocrine glands

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7
Q

what are the main three phases of the hair cycle and what happens when

A

Anagen (growing), Catagen (transition), Telogen (resting phase)

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8
Q

what are the three structures of the nasal planum

A

nares, philtrum, alar fold

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9
Q

specific autoimmune dz that only affects dogs claws. painful, brittle nails.

A

lupoid onchyodystrophy

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10
Q

what is the treatment for SLO

A

symmetric lupoid onchyodystrophy. doxy + immunomod, supplement fatty acids and pain management

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11
Q

papule vs pustule

A

papule is edema and inflam cells. pustules are purulent material.

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12
Q

raised lesion that consists of edema. (hive)

A

wheal

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13
Q

flat discoloration of the skin. ex: vitilago

A

macule

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14
Q

what is the big version of a macule

A

patch.

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15
Q

vesicle vs papule

A

vesicle contains fluid. very small. papule is edema and inflam cells.

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16
Q

big vesicle?

A

bulla. fluid filled.

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17
Q

a mast cell tumor is an example of what type of lesion

A

nodule

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18
Q

secondary lesion that does not penetrate the basement membrane

A

erosion

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19
Q

when the skin looks like tree bark. thickening of all layers. from chronic scratching

A

lichenification

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20
Q

thickening of only the stratum cornyeum. flaky

A

hyperkeratosis

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21
Q

how to tell if alopecia is primary of secondary

A

primary will have intact hairs, with the hair easily removed
secondary will have broken hair shaft ends. stronger. indistinct margins

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22
Q

keratin and sebaceous material clumped on each hair shaft

A

follicular cast

23
Q

dilated hair follicles. seen with cushings and demodicosis. blackheads

A

comedones.

24
Q

erythema vs petechia

A

erythema: redness from vasodilation. will blanch when you apply pressure
petechia: purplish. extravasation of blood. does not blanch

25
Q

two common conditions that cause hyperpigmentations

A

hypothyroidism and post-inflammation

26
Q

what are the 5 major ddx for puppies with skin issues

A

juvenile demodecosis, dermatophytosis, juvie cellulitis, puppy pyoderma, oral papillomatosis

27
Q

tx for juvie demodecosis

A

if localized, it will resolve on its own.

28
Q

tx for adult and generalized demodex

A

ixozolazines: bravecto, nexgard, simparica, credelio

29
Q

which is contagious d. cati or d. gatoi

A

d. gatoi. also extremely pruritic

30
Q

multi focal alopecia: what are some top ddx. not super itchy

A

dermatophytosis, pemphigus folliaceus, bacti epicollarette.

31
Q

dermatophytosis tx

A

topical azoles. may take months to control

32
Q

what is unique about where PF lesions are

A

on both surfaces of the ears

33
Q

what would cytology look like on Pemphigus foliaceus

A

normal neutrophils with keratinocytes. NO bacti.

34
Q

you see eosinophils in a skin cytology. what are your 3 broad ddx

A

parasites, hypersensitivity, mast cell tumor

35
Q

skin scrape reveals degenerate neutrophils with intracellular bacteria.

A

pyoderma

36
Q

you do a cytology of an ear and find yeast. is it significant

A

if you find .5-1 yeast/HPF with clinical signs, this is significant

37
Q

what three ectoparasites can you find on a trichogram

A

cheyletiella, demodex, and lice

38
Q

what rod is always a concern found in bacti culture and may require sus testing

A

pseudomonas arugenosa

39
Q

cytology with macrophages and lymphs suggest what

A

deep, chronic lesions. deep pyoderma

40
Q

cytology reveals nondegenerate neutrophils with no bacteria. what are the three ddx

A

pemphigus foliaceus, primary allergic rxn, irritant rxn

41
Q

skin lesions are bilateral. what does that suggest? what if theyre asymmetrical

A

bilateral/symmetrical: systemic, hypothyroidism, PF
asymmetrical: ectoparasites, fungal, surface things

42
Q

firm nodules on muzzle, eyes and face. may be painful. common in puppy

A

juvie cellulitis

43
Q

lesions are annular. 3 ddx

A

superficial pyoderma, demodicosis, dermatophytosis

44
Q

intensely itchy papules on edges of pinna

A

sarcoptes mange

45
Q

superficial pyoderma that does not have pustules. only spreading collarettes

A

exfoliative pyoderma.

46
Q

general tx for widespread pyoderma

A

tetracyclines, clindamycin, cephalosporins, clauvamox, reserve fluoroquinolones if other treatments are not working

47
Q

how do you dx hypothyroidism from hyperadrenocorticism

A

cushings has: comedones, symmetric alopecia
hypothyroid has: friction alopecia and hyperpigmentation

tt4, acth, cbc/chem

48
Q

drug of choice for cushings

A

trilosane

49
Q

what is the treatment for most hair cycling abnormalities causing alopecia

A

no treatment. maybe microneedling?

50
Q

clinical signs that distinguish D. canis from D. injai

A

D. injai are longer and inhabit the sebaceous glands so the coat is really greasy.

51
Q

how to diagnose dermatopathy

A

biopsy

52
Q

tx for generalized dermatopathy or dermatomyositis

A

cyclosporine

53
Q

treatment for pemphigus foliaceus

A

oral prednisone/olone until no new lesions.

+ azanthioprine or cyclosporine if pred isnt cutting it alone