drugs exam 2

Question 1

which MAOI is in the CNS and anipryl acts on?

Answer 1

MAO-B

Question 2

uses of selegiline?

Answer 2

improve spatial memory. selective action on MAO-B, stops breakdown on NT-serotonon

Question 3

fluoxetine requires_______ wash out period? between what drugs?

Answer 3

5 week washout period. can’t use selegiline within two weeks of TCAs or SSRIs

Question 4

what is the action of TCAs? drug name?

Answer 4

NE reuptake inhibition? clomipramine-most specific

Question 5

with TCAs and SSRIs, you must be careful with what types of dogs?

Answer 5

epileptic and diabetic dogs

Question 6

SNRI? drug name?

Answer 6

serotonin NE reuptake inhibitors, venlafaxine

Question 7

which behvior mod drug is antipruritic

Answer 7

TCAs -clomeprimine

Question 8

can you combo TCA adn SSRI

Answer 8

no. you need a full washout period with them

Question 9

trazodone: who do you use it in?

Answer 9

dogs cats and horses. individualized dose for each animals.

Question 10

IV traz?

Answer 10

no

Question 11

trazodone adverse effects in hoses

Answer 11

muscle fasiculation and arrhythmias around anesthesia. dont give 24h post anesth

Question 12

calcium channel blocker

Answer 12

Gabapentin: anticonvulsants, pain meds, antianxiety

Question 13

alpha-2 agonists? which method? use?

Answer 13

transmucosal. only used to chill animals only. not a preanseth. dexmedatomidine

Question 14

nonFDA products?

Answer 14

gabapentin (Ca blocker), traz (SARI), diazepam (benzo), alprazolam (benzo)

Question 15

benzodiazepine, SARI, alpha2agonist, ca channel blocker

Answer 15

adjunctive use, episodic