Skin Structure and Function 2 Flashcards
What is the dermo-epidermal junction?
interface between the epidermis and dermis
what are the two main fucntion of the junction
support and anchorage for growth and differentiation of epidermal cells
semi-permeable membrane
Name an inherited disease of the DEJ
epidermolysis bullosa (simplex or dystrophic)
Name an acquired disease of the DEJ
pemphigus, pemphigoid, dermatitis herpetiformis
Name the main components of the dermis
celss- fibroblasts, macrophages, mast cells, lymphocytes and langerhans
collagen and elastin fibres
ground substance
blood vessels, lymohatics, nerves
what do fibroblasts do
secrete collagen
describe the flow of blood in the skin
arteriole- pre capillary schincter- arterial capillaries- venous capillaries- post capillary venules- collecting venules
what is an angioma
localised overgrowth of blood vessels
name the two special nerve receptors in the skin and their functions
pacinian (pressure)
Meissners (vibration) corpuscles
name the three types of skn glands
eccrine
apocrine
sebaceous
where are most sebaceous glands located
face and chest
what do sebaceous glands produce
sebum (squalen, wax estr, triglyverides and free fatty acids
what is the function of sebaceous glands
control moisture lost
protection from baterial and fungal infection
where are apocrine glands present
axillae and perineum
What is the function of appocribe glands
produce oily fluid
androgen dependent
