Skin Structure and Function 1 Flashcards
Where does the epidermis come from?
Ectoderm
Where does the dermis origniate?
Mesoderm
Where do melanocytes originate?
neural crest
What is gastrulation?
cellular organisation into germ layers
when does gastrulation occur
days 7-10
Name the skins layers at four weeks
periderm
basal
dermis
name the skin layers at 16 weeks
keratin granular prickle cell basal dermis
What are blaschko’s lines?
developmental growth pattern of skin - not following vessels or nerves or lymphatics
What does the skin constist of
epidermis appendages (nails, hair, glands, mucosae) dermo-epidermal junction dermis sub-cutis
What kind of epithelium is in the epidermis
stratified squamous
name four other types of cells in the epidermis
keratinocytes
melanocytes
merkel cells
langerhans
how many layers are in the epidermis
four
name the four layers of the epidermis
keratin
granular
prickle cell
basal
name two conditions in which there is loss of balance in epidermal cell turnover
skin cancer
psoriasis
how long does it take for keratinocytes to move from the basement mebrane to the top
28 days
