Passmedicine/Pastest Flashcards
what is acanthosis nigricans
Describes symmetrical, brown, velvety plaques that are often found on the neck, axilla and groin
associated with insulin resitance
causes of acanthosis nigricans
diatbetes acromegaly cushings PCOS gastrointestinal cancer obesity hypothyroidism familial Prader-Willi syndrome drugs: oral contraceptive pill, nicotinic acid
causes of spider naevi
liver disease
pregnancy
combined oral contraceptive pill
features of pyoderma gangrenosum
initially small red papule
later deep, red, necrotic ulcers with a violaceous border
may be accompanied systemic symptoms e.g. Fever, myalgia
causes of pyoderma gangrenosum
idiopathic in 50% inflammatory bowel disease: ulcerative colitis, Crohn's rheumatoid arthritis, SLE myeloproliferative disorders lymphoma, myeloid leukaemias monoclonal gammopathy (IgA) primary biliary cirrhosis
management of pydoderma ganrenosum
steroids
other immunosuppresives 2nd line
bacteria associated with acne
Propionibacterium acnes
most aggressive type of melanoma
nodular
most common type of melanoma
superficial spreading
causes of erythema nodosum
TB, strep infections
sarcoidosis, IBD, Behcet’s, malignancy
Medications- COCP, peneclillins , sulphonamides
Pregnancy
what causes a blue naevus
melanocytes fail to fully migrate to epidermis and so are stuck deeper down in the dermis giving a bluish colour
what is asteatotic eczema
dermatitis which occurs on very dry skin
classically elderly and malnourish people which transfered into a warn environment eg hosptital
;crazy paving pattern
what is erythema nodosum
inlfammation of the subcutaneous fat
what must you always ask about during eczema history or review
SLEEP
school/work problems
mood
bullying/embarassment/psychological problems
what is the typical history of a pitirysis rosea
herald patch intially followed by widespear truncal rash of multriple erythematous papules with peripheral scale
often follows a viral infection