Skin Pathology

Question 1

What is lichen planus? Caused by? Causes what in the mouth?

Answer 1

Purple polygonal papules on skin. Immune mediated. Causes lacy lesions called Wickhams Striae and leukoplakia in the oral cavity.

Question 2

What is Pemphinigus Vulgaris? Cuased by? What is a common feature?

Answer 2

Superficial bullae that easily rupture in Mouth then skin. Caused by antibodies against cellular junctions. Feature is Acantholysis=floating keratinocytes

Question 3

What is Bullous Pemphigoid? Caused by? At risk?

Answer 3

Big, subepidermal bullae of groin, arms, and mouth. Caused by Antibodies against basement membrane. Elderly at risk.

Question 4

What is Melanoma? What increases risk? What is it called in mouth?

Answer 4

Malignant tumor of melanocytes. Risk increased by sun exposure. Called Acral Lentiginous in the mouth.

Question 5

What is basal cell carcinoma? Manifestation? Risk?

Answer 5

Malignant tumor or basal layer. Pearly nodule. Older, Sun exposure.

Question 6

What is squamous cell carcinoma? Risk? Manifestation?

Answer 6

Malignant tumor of squamous epithelium. Older, Sun exposure. Red nodule.

Question 7

What is Actinic Keratosis? Risk? Manifestation?

Answer 7

Benign neoplasm of epidermis. Rough spots with erythematous base. Sun exposed skin.