Inflammation

Question 1

What is the main effect of inflammation?

Answer 1

Increased vasodilation and vascular permeability.

Question 2

What is the major mediator of imflammation vessel changes? What cell makes this?

Answer 2

Histamine. Mast cells and Basophils

Question 3

What is the steps that leukocytes take in order to get to the site of injury? Mediated by what molecules?

Answer 3

1. Margination and rolling (Selectins)
2. Adhesion
3. Transmigration (Integrins)
4. Chemotaxis

Question 4

What protein leads to opsonization in inflammation?

Answer 4

C3b.

Question 5

What cells infiltrate during chronic inflammation?

Answer 5

Monocytes/Macrophages and lymphocytes

Question 6

WHat is Classic M1 response in inflammation?

Answer 6

Microbicidal actions and inflammation.

Question 7

Describe a monocyte?

Answer 7

Large, oddly shaped cell with a nucleus that does not fill the cellular space.

Question 8

Describe a Lymphocyte?

Answer 8

Cell with nucleus that mostly fills the cellular space.

Question 9

Describe a Neutrophil.

Answer 9

Polymorphic nucleus cell with few granulocytes

Question 10

Describe a Eosinophil.

Answer 10

A polymorphic nucleus cell with many RED granulocytes

Question 11

describe a Basophil.

Answer 11

A polymorphic nucleus with many BLUE granulocytes.