Silico Tuberculosis Flashcards
1
Q
Pathogenesis
A
Macropgaes engulf- phagolysosome
Cm damage - other macrophage take up - same
Tnf alpha - fibrosis
Fibrosis interfere with clearance of mtb
Humaral and cell mediated immunity absent
2
Q
Radio
A
Nodule apical lobe doesn’t cross fissure
Silicotic nodule with cavitation
Sputum. Bronch,tblb
3
Q
Rx of silico tb
A
Ipt for 1yr
Limit exposure
Periodic cxr and tuberculin test
