Congenital Tb Flashcards

1
Q

Mode of transmission in congenital tb

A

Via umblical vein- comolex in liver and ln
Aspiration of af- multiple complexes in git , ear , lung
Direct contact with lesion whole delivery

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2
Q

Diagnostic criteria

A

Beitzke

Cantwell beitzke

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3
Q

Beitzke

A

Isolation of mtb from infant
Primary complexin liver
If absent complex- tb diagnosis jn days after birth
Absence of contact with tb after birth

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4
Q

Clinical features

Pbysical

A
Resp distress
Lethargy
 poor feeding 
failure to thrive
 fever
 irritability 
hepatosplenomegaly
 lymph node 
jaundice
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5
Q

How do you diagnose congenital Tb

A

History
radiology chest X-ray USg CT mri culture from gastric washings biopsy from liver, ln ,skin ,bone marrow ,spinal fluid, phage typing

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6
Q

How can be phage typing used to diagnose congenital Tb

A

It differentiats whether the mycobacteria isolated from mother and the Infant

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7
Q

Mx of congenital tb

A
All infants born to mother with active tb- should be screened
If neg- inh 5mg/kg /day for 6 months 
At 3month- screening
If tst negative- give bcg
If positive and asymp- continue 
If symptomatic- qtt
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