Congenital Tb Flashcards
Mode of transmission in congenital tb
Via umblical vein- comolex in liver and ln
Aspiration of af- multiple complexes in git , ear , lung
Direct contact with lesion whole delivery
Diagnostic criteria
Beitzke
Cantwell beitzke
Beitzke
Isolation of mtb from infant
Primary complexin liver
If absent complex- tb diagnosis jn days after birth
Absence of contact with tb after birth
Clinical features
Pbysical
Resp distress Lethargy poor feeding failure to thrive fever irritability hepatosplenomegaly lymph node jaundice
How do you diagnose congenital Tb
History
radiology chest X-ray USg CT mri culture from gastric washings biopsy from liver, ln ,skin ,bone marrow ,spinal fluid, phage typing
How can be phage typing used to diagnose congenital Tb
It differentiats whether the mycobacteria isolated from mother and the Infant
Mx of congenital tb
All infants born to mother with active tb- should be screened If neg- inh 5mg/kg /day for 6 months At 3month- screening If tst negative- give bcg If positive and asymp- continue If symptomatic- qtt