Iris

Question 1

What is Iris

Answer 1

Extreme immune response against Dead Or live mtb

Question 2

What are the risk factors for Iris

Answer 2

Shorter interval between ATT and arv
 CD for less than 50 
higher baseline viral load greater increase in cd4
disseminated Tb
young male

Question 3

What is the pathogenesis of iris

Answer 3

Increase antigen in disseminated kochs plus risk factors shift the th2 response to th1 response release of inflammatory cytokines causing Iris

Question 4

What are the symptoms of iris

Answer 4

Paradoxical deterioration of Tb symptoms and radiological finding after initial improvement
it is a diagnosis of exclusion

Question 5

What are the types of iris

Answer 5

Unmasking
paradoxical
cryptic
autoimmune

Question 6

What is Un masking

Answer 6

ASymptomatic in the beginning , later unmasks the inflammation

Question 7

What is paradoxical Iris

Answer 7

It is the most common type aggravation of the existing inflammation

Question 8

What is cryptic iris

Answer 8

Radiological worsening is there but there are no symptoms

Question 9

What is the kind of iris scene in HIV

Answer 9

Both paradoxical and un masking form
there is major pulmonary involvement TB
Meningitis in 5 to 10 months abdominal TB