Hsn Rxns To Att

Question 1

Mild

Answer 1

Flushing without rash- 2-3 hrs - anti histamine

With or without rash ,hot flushes/headache/bp- inh+ tyramine containing food

Question 2

Moderate severe hsn rxn

Answer 2

Raised itchy rash + fever

Hrz cyc e

Question 3

Child with hsn rxn

Answer 3

Stop
Rule out viral
If positive- restart
Dont rechallenge

Question 4

Mx in adults

Answer 4

Stop
Rechallenge after 4 days
Smaller dose then full dose
If sever 1/10th dose 
Double dose & bd - at full dose bd for 3 days n then od

Question 5

What if rxn during desensitization

Answer 5

Decrease to the previous toleerated dose and increase in small doses