Sievert GI Embryology Flashcards

1
Q

Lateral and rostal caudal folding incorporates both the (blank) and (blank) into the embryo.

A

gut tube and coelom

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2
Q

(blank) are incorporated into the body cavity during folding.

A

2 coelomic cavities

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3
Q

The (Blank) is supported between the lining of the two coelomic sacs.

A

gut tube

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4
Q

What is the lining of the coelomic sacs called?

A

mesentary

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5
Q

Initially there is what kind of mesentary? What happens to it?

A

there is a dorsal and ventral mesentary the entire length of the gut tube.
The ventral later deteriorates through most of the tube

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6
Q

As folding progresses the yolk sac gets pinched down to form a (blank).

A

gut tube

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7
Q

As folding progresses the yolk sac gets pinched down to form a gut tube with a (blank) connecting to the remaining yolk sac

A

stalk (vitelline duct)

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8
Q

The mucosa and glands of the GI tract arise from the (blank) and the surrounding CT and SM comes from (blank) .

A

endoderm

splachnic mesoderm of the lateral plate

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9
Q

What is the lining of the coelomic sacs from each side of the gut tube and is the pathway for vessels and nerves to reach abdominal organs?

A

mesentaries

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10
Q

Do we always have mesentaries?

A

no, they persist only when necessary

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11
Q

What is 2 layers of peritoneum with invested nerves and blood vessels?

A

mesentary!

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12
Q

Why do we have ventral mesentary in some places but not others?

A

because in some places we have structures that are anterior to the gut tube developmentally such as the liver, gall bladder etc. You need a mesentary here to support the development of these.

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13
Q

Where do you need to maintain a ventral mesentary (discontinuous)?

A

the foregut

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14
Q

When do you have a continuous mesentary?

A

when you have no ventral mesentary

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15
Q

Anywhere below the foregut (midgut or hindgut) what kind of mesentary will you have?

A

continuous

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16
Q

What region undergoes rotation that takes the ventral mesentary and creates the greater curvature of the stomach?

A

the foregut

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17
Q

The dorsal mesentary is found throughout the entire length of the abdominal gut tube, but the ventral mesentary is only found in the region of the (blank) where it supports the liver and gall bladder.

A

foregut

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18
Q

The (blank) and the (blank) represent the two components of the ventral mesentary that remain in the adult.

A

the lesser omentum and the falciform ligament

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19
Q

The (blank) is important because it supports the umbilical vein.

A

falciform ligament

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20
Q

What is the only way to get into the right coelomic sac in the region of the foregut?

A

through the epiploic foramen

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21
Q

Is there anything in the periotoneal sac?

A

no

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22
Q

What does intraperitoneal mean?

A

sandwiched between continuous peritoneum

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23
Q

Where is there continuous mesentary?

A

midgut and hindgut

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24
Q

What does it mean to be peritonealized?

A

it is intraperitoneal

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25
Although most of the gut tube has a mesentary initially, some structures (blank) their mesentary during future development
lose
26
Structures that never have a mesentary are primarily (blank).
retroperitoneal
27
Structures that lose their mesentary are (blank)
secondarily retroperitoneal
28
Are these primarily or secondarily retroperitoneal? | distal portion of rectum, anal canal, kidneys, UG system, thoracic esophagus.
Primarily retroperitoneal
29
Are these primarily or secondarily retroperitoneal? | pancreas, ascending and descending colon, duodenum.
secondarily retroperitoneal
30
What is the artery to the foregut?
the celiac trunk
31
What is the artery to the midgut?
superior mesentaric
32
What is the artery to the hindgut?
inferior mesentaric
33
Where does the midgut end at and where is it at?
the left colic flexure (just like vagus) | Goes to the rest of duodenum to the distal third of transverse colon.
34
Where is the foregut at?
just past the opening of the bile duct and pancreatic duct in the duodenum
35
Where does the hindgut end?
distal third of transverse colon to the proximal anal canal
36
The stomach undergoes a 90 degree rotation with the (blank) surface turning to the right and the (blank) surface turning to the left. What happens to the ventral mesentary?
anterior (lesser) posterior (greater) Moves to the right
37
Which surface of the stomach is the lesser curvature?
the anterior
38
As the greater curvature of the stomach undergoes expanded growth, the dorsal mesentary needs to expand to accomodate both the growth and expansion. This expansion creates the (blank).
greater omentum
39
The space behind the lesser omentum is known as the (blank)
lesser sac
40
The space behind the lesser omentum (lesser sac) retains a small area of continuity with the greater sac through an opening know as the (blank)
epiploic foramen
41
The greater omentum is made up of (blank) layers of mesentary
four
42
dorsal mesogastrium is the same things as (blank) | the omental bursa is the same thing as (blank)
dorsal mesentary | lesser sac
43
What is the ligament that connects the liver to the body wall?
falciform ligament
44
What is the mesentary from the stomach to the liver?
lesser omentum
45
The liver, gall bladder, and ventral pancreatic buds are all attached to the (blank) at the same place. There is a separate dorsal pancreatic bud!
duodenum
46
Differential growth and rotation in the wall of the duodenum moves the opening of the bile duct around to the (blank) surface.
dorsal
47
Although the two pancreatic buds have separate ducts at the beginning of development, the duct forming the dorsal bud eventually merges with the duct from the ventral bud with often only a short (blank) remaining.
accessory duct
48
The twisting that the ventral pancreas undergoes can cause (blanK)
a constriction
49
The midgut loop is centered on the (blank) with the cecum, ascending and transverse colon in the caudal half of the loop.
superior mesentaric artery
50
How does the midgut loop rotate?
counterclockwise 270 degrees
51
THe rotation of the midgut around the superior mesentaric artery results in what part of the gut getting trapped under the SMA?
the duodenum
52
The midgut rotation causes the (blank) to frame the small bowel around the periphery and puts the (blank) in the lower right quadrant and the (blank) on the left side.
colon cecum descending colon
53
The rostral portion of the (blank X 3) will rotate counterclockwise within the midgut rotation
cecum, ascending and transverse colon
54
Completion of the midgut rotation takes place in the (blank)
abdomen
55
The completion of rotation begins at the (blank) when the midgut begins to reenter the abdomen.
10th week
56
The early rotation takes place (blank) of the fetus because of the rapid growth of the tube relative to the fetus. The final completion of rotation takes place in the abdominal cavity
outside
57
Any form of rotation of parts of the gut tube can be dangerous because of the potential for (blank).
disrupting blood supply and causing gangrene
58
(blank) is an abnormal rotation and can be caused by many different pathologies like surgical adhesions, abnormal rotations etc.
volvulus
59
(blank) is when the lateral walls of abdomen do not close completely. The expanding GI tract protrudes through this opening. (common in cocaine using moms). Survival rate is good. Herniation is not covered by amnion and are exposed to amniotic fluid.
gastroschisis
60
(blank) is a herniation of abdominal viscera through an enlarged umbilical ring. There was a failure of the intestinal loops to return to the body cavity from the umbilical cord after normal physiological herniation. These are covered with epithelium of umbilical cord (amnion). Associated with severe defects and mortality. Bowel loops not exposed to amniotic fluid
Omphalocele
61
What is when your Gi tract grown outside your body? Is it exposed to amniotic fluid?
gastroschisis | yes
62
What is a herniation of bowels? Is it exposed to amniotic fluid?
omphalocele | no
63
What is the most common GI developmental abnormality?
Meckel's or ileal diverticulum
64
Most common GI developmental abnormality (Meckel's or ileal diverticulum) results when a small portion of the (blank) persists.Occurs in 2% to 4% of all people; asymptomatic. Because it is a diverticulum, in the adult, there may be ulceration, bleeding or perforation.
vitelline duct
65
What is the rule of 2 that Meckel's follows?
2% of pop, 2 feet from ileocecal valve, 2 inches in length, 2% symptomatic, 2 types of common ectopic tissue (gastric and pancreatic),2 years is most common age, 2 times more common in males
66
What exists in many forms and can cause a variety of strangulation problems?
rotation anomalies
67
What is the pectinate line?
the separation between endoderm and ectoderm derivatives.
68
The endodermal portion (hindgut) of the anal canal is innervated by (Blank). Does it sense pain? The ectodermal portion (proctode) of the anal canal is innervated by (blank). Does it sense pain?
ANS, No | Cutaneous nerves, yes
69
(blank) is a failure of migration of neural crest cells into the developing gut tube. Usually affects the rectum and sigmoid colon and results in a section of the gut tube which is lacking ganglia and unable to contract.
Hirschsprung disease or aganglionic megacolon