Side effects of some drugs

Question 1

ACEi known to cause renal impairemnts what shoudl you check on dose change or stating drug

Answer 1

serum creatinine

Question 2

what electrolyte abnormality can ACEi cause - either due to direct inhibtiion of renin angiotension aldosterone system or indirectly through renal impairment

Answer 2

high potassium

can also cause low sodium

potassium more important to check

Question 3

beta blocker side effects - common

Answer 3

dry eye
erectile dysfucntion
fatigue
bradycardia
cold extremeties

Question 4

what causes tremour BB or salbutamol

Answer 4

salbutamol

BB treat essential tremor and anxiety induced tremor

Question 5

abdo pain and black stool caused by what drug exmaple

Answer 5

upper gi bleed so thinking GI ulcer

naproxen adn other NSAID

Question 6

how do NSAID cause peptic ucler

Answer 6

inbhitb prostoglandin synthesis needed for gastric mucosal protection from acid

Question 7

how to steriods cause peptic ulcers

Answer 7

inhibit gastric epithelial renewal thus predisposing to ulceration

Question 8

how do NSAID cause renal impairment

Answer 8

by acute interstitial nephritis - rise in creatiine

Question 9

is NSAID induced nephrotoxicity more likely to occur in patients with pre-existing renal impairment

Answer 9

yes

Question 10

should prescribe ACEi and NSAID together and reason

Answer 10

no

ACEi - relax efferent vessels - this decreases renal pressure protecting renal vessels from hypetension. as a conseuqence of this EGFR will drop

NSAID - inhbit prostaglndins so constrict afferent vessels reducing flow to kidney lowering pressure so lowering EGFR

Question 11

istin is what drug

Answer 11

CCB

Question 12

motifene is what drug

Answer 12

diclofenac

Question 13

jylamvo trade name for

Answer 13

methotrexate

Question 14

dropping neutrophil count caused by what drug with methotraxate

Answer 14

co -trimoxazole as contains trimethoprim - folate natagonist - bone marrow suppression

Question 15

what drug to reverse effects of heparin

Answer 15

protamine

Question 16

augumentin brand name for

Answer 16

co-amoxcilva

Question 17

with AF and noticed haemautria what abx may have caused this

Answer 17

erythromycin as inhbitor assuming they are on warfarin as chadvasc score done for AF

Question 18

ACEi what do you need to check

Answer 18

electrolytes as potassium can rise

Question 19

side effect of beta blockers

Answer 19

fatigue

Question 20

what drugs cause peptic ulcers and gastric muscoal irritation

Answer 20

nsaid such as ISTIN - naproxen adn steriods

Question 21

what is motifene more commonly known as

Answer 21

diclofenac

Question 22

first thing to do in anaphylaxis management

Answer 22

secure airway

Question 23

n