All most important things from notes and mocks that you need to remember Harry Flashcards

1
Q

common cause or urticara

A

aspirin

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2
Q

when can you not give sumatriptan

A

hx of hypertension and high BP

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3
Q

if you cant give sumatriptan what do you give instead for migraine

A

aspirin or ibuprofen

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4
Q

resus fluids in a child

A

sodium chloride 10ml/kg

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5
Q

two drugs contributing to postural hypotension

A

flozins and BB

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6
Q

what medications should you suspend in a suspected head injury

A

anything causing bleeding - antiplatelet , anticoag
drowsines and confusion drugs - amitritpylline sand zopilcone - would be problematic in context of acute head injruy

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7
Q

dexamethasone prescirbed at night why might this be a problem

A

can cause insomnia if night that is why normally prescribed in the morning

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8
Q

gestational diabetes what tx summary can you find it in

A

diabetes pregnancy and breast feeding

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9
Q

in what drug next - what should you check

A

check they are on optimal doses of that drug thus meaning they are on the maximum or if you can give them another

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10
Q

hypercalcaemia what do you treat with

A

sodium chloride IV 1ltr over 4hrs

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11
Q

post emergency contraception what should happen

A

preg test

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12
Q

wiht iron supplementation what is the most important info

A

dont take calcium and iron together

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13
Q

considered does mean defo measure

A
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14
Q

what feature suggest heaptic necrosis in paraceamol overdose

A

RUQ tenderness

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15
Q

during mineralcortiocid therap what needs to be measured

A

UandE - k and na , bp fluid balance

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16
Q

what things are useful to monitor benefits of treatemnet and assess effectiveness

A

self reporting of symtpoms severity and freqeyncy

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17
Q

best way to measure a ong acting insulin to tittrate up

A

monitor pre breakfast fasting capillary blood glucose

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18
Q

somone not maintainign sats on 24% venturi mask what do you do

A

chnage to 28% venturi
given that oxygen saturation is below the limit - fio2 should be increased under controlled conditions

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19
Q

normal strength of novarapid

A

100 units/ml

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20
Q

A 44-year-old man is admitted to the acute medical unit diagnosed with acute coronary syndrome. He usually takes 140inits of insulin degludec (Tresiba 200inits/ml) twice daily and Novorapid with meals. The insulin is unavailable overnight and he has forgotten his pen device. What is the most appropriate course of action?

A

Administer 140 units of insulin Tresiba (100units/ml)

never chnage the dose just the concentraiotn as it just a differenence in volume

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21
Q

You are the FY1 on call overnight. You are asked by nursing staff to review a patient with type 1 diabetes mellitus who has suffered from hypoglycaemia at 0700. He takes Lantus 20 units at night and a variable dose of Humalog with meals. He has had a carbohydrate snack and his CBG is now 4.5mmol/l. What is the correct course of action?

A

Give usual dose of Humalog with breakfast

stiill give usual insulin dont change the regime

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22
Q

A 78 year-old lady who lives with her daughter is admitted with general decline. Her daughter administers the patients twice daily insulin dose at 0800 and 2000. The dose is 40 units twice daily. She reports that her mother has had repeated overnight hypoglycaemia. What should you prescribe on the insulin chart?

A

Reduce evening insulin dose by 20%
rule of thumb adjust by 20% fro hypos
hypers can be 10%

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23
Q

A 64 year old man is admitted electively the evening before a right hemi-colectomy. He is taking once daily insulin lantus (glargine) at 2200 at a dose of 50 units. What is the correct course of action?

A

Prescribe 40 units lantus at 2200
surgery rule of thumb drop by 20%

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24
Q

Following left mastectomy a 55 year-old woman with type 1 diabetes is feeling ready to eat lunch. She is on VRII (Variable rate insulin infusion). The capillary blood glucose is 6.8mmol/l. She has had an appropriate dose of long acting insulin the previous evening. She usually takes Apidra (insulin glulisine) with meals. What is the correct course of action?

A

Give Apidra with lunch and stop VRII 30 minutes later

long acting is always continued alongside VRII - short actings have a 15-30min onset of action which is also why we ask to inject before meals - there needs to be an overlap period

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25
Q

A75-year old man is admitted to hospital. He takes Insuman basal 40 units twice daily for type 2 diabetes mellitus. His insulin pen device is broken and the same insulin is unavailable that evening. What is the most appropriate course of action?

A

Administer 40 units of an alternative intermediate-acting insulin such as Insulatard.

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26
Q

do bisphosphonates cause reducting in kindey function

A

yes

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27
Q

2 meds that contribute to anoxeria

A

metoformin
rivastigmine

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28
Q

more likely to cause dka SGLT-2 or insulin

A

SGLT-2

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29
Q

montior adverse affects of ceft

A

FBC

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30
Q

how quickly does fertility return with the implant

A

straight away

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31
Q

sumatriptain muscle se

A

muscle ache

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32
Q

on inuslin infusion waiting for surgery what do you give with

A

%5 dextrose with potasium over 8-12hr

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33
Q

beneficial monitoring parameter in addisions disease with someone on hyrdrocortisone

A

weight

not serum cortisol as this would depend on when you take the steriods

34
Q

nephrotoxic drugs

A

NSAID
acei
vancomyin
aminoglycosides
ciclosporin
tacrolimus
zoledndroni acid

35
Q

hepatotoxic drugs

A

coamox
amiodarone
methotrexate
valp
isoniazid
rifampicin

36
Q

pancreatitis

A

valp
liraglutide
DDP4 i - gliptiins

37
Q

blood dyscrasis and disorders - seek immediate help if sx fever rash outh ulcers, bleeding burising

A

carbamazepine
aminosalicylates
lamotrigine
valp
carbimazole
phenytoin
methotrexate
trimethoprim

38
Q

doxy advice

A

swallow with plenty of fluid

39
Q

GTN tablets discard when

A

after 8 weeks

40
Q

how long do you need to take levo before caffine and break

A

30 mins

41
Q

how do you take phenytoin

A

with or after food

42
Q

do you have to take warfarin at the same time each day

A

yes and dont make major changes in die or alcohol consumption

43
Q

smoking cessation increase the concentration of what drugs

A

theophylline and antipyshcoics and ropinerole

44
Q

peak level to high

A

reduce dose but keep same freq

45
Q

trough level to hihg

A

increase itnerval between dosese eg TDS to BD

46
Q

what drugs taken in morning

A

diuretics and steriods

47
Q

what drugs taken in evening

A

statins and sedatives

48
Q

intercurrent illness what do you do to steriods

insulin

and sglt2

A

double

reduce

hold sglt2

49
Q

galactorrhea causing meds

A

metoclopramide
olanzapine
citalopram

50
Q

surgery and diabetes what do you do

A

reduce long acting dose t 20%

51
Q

metformin surgery

A

day before and day of unlesss TDS so hold post break

52
Q

gliclacizde surgery

A

held day of

53
Q

what drugs need stopping before surgery

A

insulin lihtum anticoag cocp hrt
k sparing diuretics
oral hyoglycaemiacs
adn acei

54
Q

for pain always start with - esepcially even if eldery in neuropathuc pain

A

paracetamol

55
Q

how much hydrocrotisone shoudl you take in surgery if you have been taking long term pred

A

25-50 mg

56
Q

do patches take time to work

exmaples

A

yes

morphine, fent , buprenorpine and oxycodone

57
Q

does doxycylcine affect cocp taking

A

no

58
Q

precipitants of c.diff

A

omeprazole, low mg , low na , co-amox
ciprofloxacin, cindamyicn , cephalopsporin

59
Q

ck raised in

A

neuroleptci laignnat syndrome

and myositis

60
Q

dose of sri in preg

A

lowest dose possible

61
Q

emergency resus fluid

A

bolus NaCL 500ml 10min
250 in old or HF

62
Q

emergnecy hypercal

A

nacl 0.9% 1L 4hr

63
Q

emergency hypog fluid

A

glucose 10% 200ml 15min
or
glucose 20% 100ml 15min

64
Q

emergency hypok

A

nacl 0.9% / kcl 0.3% in 4hr 1L

65
Q

maintainance fluids no losses

A

8-12hr

66
Q

maintianace fluid with losses

A

replace in 4-6hr

67
Q

children emergency resus fluid

A

nacl 0.9% 10ml/kg 10min

68
Q

maintaince fluids in kids

A

100/50/20 for each 10kg incriment

69
Q

examples of cyclical with uterus hrt regimnes

A

evorel sequi

elleste duet

70
Q

examples of continuous regimes for HRT

A

evorel conti - patch
elleste duet conti
kliofem

71
Q

no uterus what do i give

A

elleste solo or tibolone

72
Q

enzyme inducers PCBRASS

A

phenytoin
carbmazepne
barbituates
rifampicin
alcohol - chronic
sulphonluyeras
smoking

john wart
topiramate

73
Q

enzyme inhibtors sickface.com

A

sodium valp
isonisazid
cimitedine
ketoconazole
fluconazole
alchol acute and grapefruit
chloremphicol
erthymocin
sulphonamide

ciprofloxacin
omeprimazole
metronidazole

74
Q

se metformin

A

egfr stop under 30
n v
diarrhoea

75
Q

ddp4 - gliptins se

A

pancreatiits and nasopharyngitis

76
Q

piolitazone se

A

heart failure
bladder cancer
oedema
post menopausal op
weight gain

77
Q

sulphonylurea se

A

hypo
weight gain

78
Q

sglt2 i se

A

DKA
gential infection
forneuier

79
Q

glp-1 agonist exantide ,seraglutide se

A

panreaciits
weight loss
n and v

80
Q

examples of basal insulin

A

lantus humulin

81
Q
A