flashcard pharmacist revision
levythyroxine how do you have to take it
empty stomach before food or other meds
mebeverine consuellign hwat do you have to do
take just before food -20mins
drugs that cause diarrhoea - CALM D
colchine, abx, laxatives, magnesium cotnrinaing antacides and digoxin
drugs cause constipation
aluminium, antimuscariins, antihistamines, antiepileptics, verapamil, opiates, clozapine
three aromotase inhibitors
letrozole
exemestane
anastrozole
side effects of armotase inhibitord - aromatase
alopecia
reduced memory
OP
mood change
arthralgia
taste altered
appetite decreased
skin reactions
excess sweating
levythryroxine usual start dose and what are its available strengths
1.6mcg/kg
cardiac or elderly 25-50mcg
only comes in 12.5,25,50,75,100
primary prevention risk statin -20mg for what groups
QRISK over 10 with DM , age 84
eGFR under 60 or albuminuria
secondary prevention atorvastatin of 80mg who needs to be on this
ACS
angina
CHD
stroke/tia
omeprazole moa
irreversibly bind to and inhibt hydrogen potassium atpase pump also known as the proton pump
can also reduce stomach acid after 5 days
side effect of PPI
OP
c diff risk
reduced b12 absorption
Subcutaneous lupus erthematous
low MG ( after 1 yer) , low sodium
dyspepsia usual maintaince dose
lansoprazole 30mg OD (omepraole 20) - use L
H pylori usual dose ppi
lansoprazole 30mg OD
what should you avoid PPI with
clopidogrel - with omeprazole - reduces clop
methtrexate
citalopram - increases level
warfarin - increased warfarin so monitor INR
ADR of salbutamol - pneumonic the name
shaky hands - tremor
arrhythmias
lactic acidosis
bronchospasm
unstable diabetes - hyperglycaemia
throat irritation
anxiety
muscle cramp
oral irritation
lightheaded - dizzy
dose of asthma salbut neb
2.5mg
why do you mix saline soluton in with nebuliser
to ease cough associated with tenacious secreations
asthma /copd inhalation of aerosaol dose of salbut
100-200micrograms up to 4 times a day
can a prolonged course of ICS trigger pneumonia
yes
bronchitis first line
doxy 200mcg 1st day then 100mg 4 day
bronchiectasis
amoxicllin 500mg TDS 7-14days
COPD exacerbation first line
amxocillin 500mg TDS 5dya
Macrolide how to know which ok in preg
clarithromycin - contraindicated
erythromycin - embryos
ADR macrolides
qt prolong
hepatotoxic
hearing
abx colitis
low potassium
drugs CI in preg
ACEi
warfarin
statin
ABX - not all
valporate
pregabalin
topiramate
bismuth
misoprostol
isotrentinoin
nsaid
mehtotraxate
mycophenolate
Long QT - long hearts make vets cut animals
lithium
haloperiodol
macrolides
venlafaxine
citalopram
amiodarone
4 pillars of drug tx in HF
ACEi
BB
spironolocatone
SGLT2i
arm if sx still instead of ace
if EF under 35 - ivarbradine
reduced EF - loop diuretic fureosmide 20-120mg or bmetanide 1.5
preserved - loop and GSLT2
BB side effects BBEACH
bradcardia
bronchospasm
eye irritation
allergic reactions
conjunctival hyperemia
hypotension
drugs that increase risk of AKI - DAMNS
diuretics
ACEi/arb
metformin
NSAID
SGLT2i
cellulitis first line
fluclox 500mcg QDS
fungal nail infections amorolfine 5% 1-2 times weekly- how long in toes and hands
hands - 6months
toes -12months
shingles tx
aciclovir 800mg 5x a day for 7 days
drugs that cause increased risk o suicidal thoughts - some medications may cause isolated feelings
SSRI
mefloquine
montelukast
corticosteriods
isotretinoin
finasteride
what hormone protects the endometrium
progesterone
quinolones suffix
floxacin
only now prescribed when other commonly recommended abx inappropriate
quinolones aDR - Q flaccid
QT prolongation
Fits
liver dysfucntion
aortic anerysm
CNS effects
cartilage damage
increased DM risk
Depression
drugs causing hyperkalaemia
Trimethorpim
ACEI
mefenamic acid
NSAID
spironolactone
hypoklaia caused by
diuretics - loop and thiazide
corticosteroids
senn
beta 2 agonists
insulin
hyponatraemia
SSRI
carbamazepine
diuretics
trimethorpim
hypercalcaemia
Vit A and D
lithium
tamoxifen
thiazides
reduced B12 drugs
PPI
colchine
metformin
SNRI used in smoking cessation
Bupropion 150mg daily increased to BD
stopped after 7w if abstinence not achieved
common side effects with SNRI
somnolence and palpitations
