flashcard pharmacist revision

1
Q

levythyroxine how do you have to take it

A

empty stomach before food or other meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

mebeverine consuellign hwat do you have to do

A

take just before food -20mins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

drugs that cause diarrhoea - CALM D

A

colchine, abx, laxatives, magnesium cotnrinaing antacides and digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

drugs cause constipation

A

aluminium, antimuscariins, antihistamines, antiepileptics, verapamil, opiates, clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

three aromotase inhibitors

A

letrozole
exemestane
anastrozole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

side effects of armotase inhibitord - aromatase

A

alopecia
reduced memory
OP
mood change
arthralgia
taste altered
appetite decreased
skin reactions
excess sweating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

levythryroxine usual start dose and what are its available strengths

A

1.6mcg/kg

cardiac or elderly 25-50mcg

only comes in 12.5,25,50,75,100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

primary prevention risk statin -20mg for what groups

A

QRISK over 10 with DM , age 84
eGFR under 60 or albuminuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

secondary prevention atorvastatin of 80mg who needs to be on this

A

ACS
angina
CHD
stroke/tia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

omeprazole moa

A

irreversibly bind to and inhibt hydrogen potassium atpase pump also known as the proton pump

can also reduce stomach acid after 5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

side effect of PPI

A

OP
c diff risk
reduced b12 absorption
Subcutaneous lupus erthematous
low MG ( after 1 yer) , low sodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

dyspepsia usual maintaince dose

A

lansoprazole 30mg OD (omepraole 20) - use L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

H pylori usual dose ppi

A

lansoprazole 30mg OD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what should you avoid PPI with

A

clopidogrel - with omeprazole - reduces clop
methtrexate
citalopram - increases level
warfarin - increased warfarin so monitor INR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ADR of salbutamol - pneumonic the name

A

shaky hands - tremor
arrhythmias
lactic acidosis
bronchospasm
unstable diabetes - hyperglycaemia
throat irritation
anxiety
muscle cramp
oral irritation
lightheaded - dizzy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

dose of asthma salbut neb

A

2.5mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

why do you mix saline soluton in with nebuliser

A

to ease cough associated with tenacious secreations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

asthma /copd inhalation of aerosaol dose of salbut

A

100-200micrograms up to 4 times a day

19
Q

can a prolonged course of ICS trigger pneumonia

A

yes

20
Q

bronchitis first line

A

doxy 200mcg 1st day then 100mg 4 day

21
Q

bronchiectasis

A

amoxicllin 500mg TDS 7-14days

22
Q

COPD exacerbation first line

A

amxocillin 500mg TDS 5dya

23
Q

Macrolide how to know which ok in preg

A

clarithromycin - contraindicated
erythromycin - embryos

24
Q

ADR macrolides

A

qt prolong
hepatotoxic
hearing
abx colitis
low potassium

25
Q

drugs CI in preg

A

ACEi
warfarin
statin
ABX - not all
valporate
pregabalin
topiramate
bismuth
misoprostol
isotrentinoin
nsaid
mehtotraxate
mycophenolate

26
Q

Long QT - long hearts make vets cut animals

A

lithium
haloperiodol
macrolides
venlafaxine
citalopram
amiodarone

27
Q

4 pillars of drug tx in HF

A

ACEi
BB
spironolocatone
SGLT2i

arm if sx still instead of ace
if EF under 35 - ivarbradine

reduced EF - loop diuretic fureosmide 20-120mg or bmetanide 1.5

preserved - loop and GSLT2

28
Q

BB side effects BBEACH

A

bradcardia
bronchospasm
eye irritation
allergic reactions
conjunctival hyperemia
hypotension

29
Q

drugs that increase risk of AKI - DAMNS

A

diuretics
ACEi/arb
metformin
NSAID
SGLT2i

30
Q

cellulitis first line

A

fluclox 500mcg QDS

31
Q

fungal nail infections amorolfine 5% 1-2 times weekly- how long in toes and hands

A

hands - 6months
toes -12months

32
Q

shingles tx

A

aciclovir 800mg 5x a day for 7 days

33
Q

drugs that cause increased risk o suicidal thoughts - some medications may cause isolated feelings

A

SSRI
mefloquine
montelukast
corticosteriods
isotretinoin
finasteride

34
Q

what hormone protects the endometrium

A

progesterone

35
Q

quinolones suffix

A

floxacin

only now prescribed when other commonly recommended abx inappropriate

36
Q

quinolones aDR - Q flaccid

A

QT prolongation
Fits
liver dysfucntion
aortic anerysm
CNS effects
cartilage damage
increased DM risk
Depression

37
Q

drugs causing hyperkalaemia

A

Trimethorpim
ACEI
mefenamic acid
NSAID
spironolactone

38
Q

hypoklaia caused by

A

diuretics - loop and thiazide
corticosteroids
senn
beta 2 agonists
insulin

39
Q

hyponatraemia

A

SSRI
carbamazepine
diuretics
trimethorpim

40
Q

hypercalcaemia

A

Vit A and D
lithium
tamoxifen
thiazides

41
Q

reduced B12 drugs

A

PPI
colchine
metformin

42
Q

SNRI used in smoking cessation

A

Bupropion 150mg daily increased to BD
stopped after 7w if abstinence not achieved

43
Q

common side effects with SNRI

A

somnolence and palpitations