flashcard pharmacist revision

1
Q

levythyroxine how do you have to take it

A

empty stomach before food or other meds

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2
Q

mebeverine consuellign hwat do you have to do

A

take just before food -20mins

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3
Q

drugs that cause diarrhoea - CALM D

A

colchine, abx, laxatives, magnesium cotnrinaing antacides and digoxin

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4
Q

drugs cause constipation

A

aluminium, antimuscariins, antihistamines, antiepileptics, verapamil, opiates, clozapine

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5
Q

three aromotase inhibitors

A

letrozole
exemestane
anastrozole

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6
Q

side effects of armotase inhibitord - aromatase

A

alopecia
reduced memory
OP
mood change
arthralgia
taste altered
appetite decreased
skin reactions
excess sweating

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7
Q

levythryroxine usual start dose and what are its available strengths

A

1.6mcg/kg

cardiac or elderly 25-50mcg

only comes in 12.5,25,50,75,100

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8
Q

primary prevention risk statin -20mg for what groups

A

QRISK over 10 with DM , age 84
eGFR under 60 or albuminuria

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9
Q

secondary prevention atorvastatin of 80mg who needs to be on this

A

ACS
angina
CHD
stroke/tia

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10
Q

omeprazole moa

A

irreversibly bind to and inhibt hydrogen potassium atpase pump also known as the proton pump

can also reduce stomach acid after 5 days

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11
Q

side effect of PPI

A

OP
c diff risk
reduced b12 absorption
Subcutaneous lupus erthematous
low MG ( after 1 yer) , low sodium

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12
Q

dyspepsia usual maintaince dose

A

lansoprazole 30mg OD (omepraole 20) - use L

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13
Q

H pylori usual dose ppi

A

lansoprazole 30mg OD

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14
Q

what should you avoid PPI with

A

clopidogrel - with omeprazole - reduces clop
methtrexate
citalopram - increases level
warfarin - increased warfarin so monitor INR

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15
Q

ADR of salbutamol - pneumonic the name

A

shaky hands - tremor
arrhythmias
lactic acidosis
bronchospasm
unstable diabetes - hyperglycaemia
throat irritation
anxiety
muscle cramp
oral irritation
lightheaded - dizzy

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16
Q

dose of asthma salbut neb

A

2.5mg

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17
Q

why do you mix saline soluton in with nebuliser

A

to ease cough associated with tenacious secreations

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18
Q

asthma /copd inhalation of aerosaol dose of salbut

A

100-200micrograms up to 4 times a day

19
Q

can a prolonged course of ICS trigger pneumonia

20
Q

bronchitis first line

A

doxy 200mcg 1st day then 100mg 4 day

21
Q

bronchiectasis

A

amoxicllin 500mg TDS 7-14days

22
Q

COPD exacerbation first line

A

amxocillin 500mg TDS 5dya

23
Q

Macrolide how to know which ok in preg

A

clarithromycin - contraindicated
erythromycin - embryos

24
Q

ADR macrolides

A

qt prolong
hepatotoxic
hearing
abx colitis
low potassium

25
drugs CI in preg
ACEi warfarin statin ABX - not all valporate pregabalin topiramate bismuth misoprostol isotrentinoin nsaid mehtotraxate mycophenolate
26
Long QT - long hearts make vets cut animals
lithium haloperiodol macrolides venlafaxine citalopram amiodarone
27
4 pillars of drug tx in HF
ACEi BB spironolocatone SGLT2i arm if sx still instead of ace if EF under 35 - ivarbradine reduced EF - loop diuretic fureosmide 20-120mg or bmetanide 1.5 preserved - loop and GSLT2
28
BB side effects BBEACH
bradcardia bronchospasm eye irritation allergic reactions conjunctival hyperemia hypotension
29
drugs that increase risk of AKI - DAMNS
diuretics ACEi/arb metformin NSAID SGLT2i
30
cellulitis first line
fluclox 500mcg QDS
31
fungal nail infections amorolfine 5% 1-2 times weekly- how long in toes and hands
hands - 6months toes -12months
32
shingles tx
aciclovir 800mg 5x a day for 7 days
33
drugs that cause increased risk o suicidal thoughts - some medications may cause isolated feelings
SSRI mefloquine montelukast corticosteriods isotretinoin finasteride
34
what hormone protects the endometrium
progesterone
35
quinolones suffix
floxacin only now prescribed when other commonly recommended abx inappropriate
36
quinolones aDR - Q flaccid
QT prolongation Fits liver dysfucntion aortic anerysm CNS effects cartilage damage increased DM risk Depression
37
drugs causing hyperkalaemia
Trimethorpim ACEI mefenamic acid NSAID spironolactone
38
hypoklaia caused by
diuretics - loop and thiazide corticosteroids senn beta 2 agonists insulin
39
hyponatraemia
SSRI carbamazepine diuretics trimethorpim
40
hypercalcaemia
Vit A and D lithium tamoxifen thiazides
41
reduced B12 drugs
PPI colchine metformin
42
SNRI used in smoking cessation
Bupropion 150mg daily increased to BD stopped after 7w if abstinence not achieved
43
common side effects with SNRI
somnolence and palpitations