prepare for the PSA instagram

Question 1

55W wants to stop smoking. Has COPD, HTN, epilepsy, AF and IBS,
select the condition that makes bupropion the most unsuitable

Answer 1

epilepsy as reduces seizure threshold due to NA and dopamine reuptake i
dont use in preg or breasftfee

Question 2

34w thick white vag discharge. ph swab 4.1

prescribe one drug that will treat this and dx

if over 4.5 thats when yu think abotu bv or trich

Answer 2

candidiasis

fluconazole 150mg PO stat

Question 3

28M asthma rev
on salbut 100mcg 2 puff PRN - not using
budesonide 200mcg 2 puff BCD

what decision do you do

Answer 3

decrease budenoside to 200mcg 1 puff BD - 25-50 % reduction

Question 4

64M left heel ache on run. worse climbing what drug caused this

Answer 4

ciprofloxacin

or steriods

Question 5

myopathy caused by what drugs (3)

Answer 5

amiodarone
colchine
statins

Question 6

22W freq of asthma sx - reg usng salbut inhaler what next

Answer 6

montelukast 10mg PO OD

Question 7

63m on salbut - obstrucitve picture
diurnal variation in peak flow
COPD
what next

Answer 7

LABA and a ICS - so salmetrol and fluticasone brocnhodialtor therapy

3rd line LABA and LAMA and ICS - trimbow inhaler

COPD treatment summary

Question 8

lmwh reversal

Answer 8

anti factor Xa and protamine sulpahte

Question 9

fondaparinux reversal

Answer 9

montior clincially and rfvilla/pcc

Question 10

what is rifaximin and when is it used

Answer 10

prophylactic agent against hepatic encephalopathy by diminishing ammonia-producing gut flora populations.

Question 11

what drug is used for acute episodes in alcoholic hepatitis

Answer 11

glucocorticoids (e.g. prednisolone) are often used during acute episodes of alcoholic hepatitis

Question 12

propjylacic abx for treatment

Answer 12

azithromycin

Question 13

dose/concentration

Answer 13

volume

Question 14

levongestrel used after how many hours

Answer 14

72

Question 15

when do you need a double dose of levongestrel

Answer 15

if BMI over 26 or weight over 70kg

Question 16

often levongestrel causes vomiting if that happens within 3hours what should happen

Answer 16

need another dose

Question 17

can you start hormonal contraception straight afte r levongestrel

Answer 17

yes

Question 18

when is ullipristal - 120hours CI

Answer 18

asthma

Question 19

incubation periods of gonorrhoea

Answer 19

2-5d

Question 20

incubation of chlamydia

Answer 20

7-21 days

Question 21

what is lymphogranuloma verenum and fetaures

Answer 21

comp of chlamydia

painless ulcer, inguinal lymphadenopathy and protocolitis in men normally treated with doxy

Question 22

options for treatment for chlamydia

Answer 22

doxy
axithromycin

Question 23

syphillis tx

Answer 23

benzathine benzylpenicllin 2.4million units IM stat

Question 24

triptan moa

Answer 24

Triptans are a class of drugs used to treat migraines that work by stimulating 5-hydroxytryptamine (5-HT) receptors in the brain. Their mechanism of action includes

Question 25

are triptans allowe in IHD

Answer 25

no as they cause vasospasm increasing risk of MI

Question 26

sx of serotonin syndrome - HARM pneumonic

Answer 26

hyperthermia autonomic excitability rigidity myoclonus neuroleptic malignant syndrome - slower onset and often a raised CK

Question 27

1% cream means

Answer 27

1g in 100ml

Question 28

1:1000 means

Answer 28

1g in 1000ml solution

Question 29

what drugs cause gingival hyperplasia

Answer 29

phenytoin tacrolimus CCBs so many people on sertrlaine and never hear about it so therefore cannot be side effect

Question 30

most important info to provide a paitent on bisphosphonates

Answer 30

they need regualar dental check ups to montior for jaw necrosis

Question 31

drug least likely to cause dyspepsia alendronic amiodarone fluoxetine naproxen pred

Answer 31

amiodarone

Question 32

what veg can turn urine red

Answer 32

rehubarb beetroot

Question 33

grapefruit has severe interactions with what drugs

Answer 33

ciclosporin tacrolimus simvastatin clopidogrel ## Footnote more of the drug enters the blood and stays in the body longe

Question 34

cranberry severe interaction with what drug

Answer 34

warfarin

Question 35

person on tranylcypromine for depression - he is advised not to eat particular foods to prevent a hypertensive crisis what can he not have of below fresh eggs grapefurit juice tinned meat marmite yoghurt

Answer 35

marmite as tyramine rich like mature cheese , salami and bovril oxo and alcohols , boad bean pods ( dopa) MOAI interations

Question 36

# 4 what drugs cause venous ulceration?

Answer 36

nicorandil corticosteroids NSAID ACEi contraindicated in critical limb ischaemia

Question 37

bisacodyl what type of laxative

Answer 37

stimulant

Question 38

what medication should be continued through illness in case of adrenal dependency

Answer 38

steriods

Question 39

when is propiothiuraicl used

Answer 39

pregnancy for hypothyroidism

Question 40

ADRs for steriods - mneumonic - steriods

Answer 40

S = Stomach ulcers * T = Thin skin * E = oEdema * R = Right and left heart failure * O = Osteoporosis * I = Infection (including candida) * D = Diabetes (especially hyperglycaemia) * S – Cushing’s Syndrome

Question 41

ADRs for NSAIDS

Answer 41

ADRs – NSAIDs (Ibuprofen, Diclofenac) * N = No urine (i.e. renal failure) * S = Systolic dysfunction (i.e. heart failure) * A = Asthma * I = Indigestion (any cause) * D = Dyscrasia (clotting abnormality)

Question 42

is aspirin contraindicated in RF, HR or asthma

Answer 42

no

Question 43

statins side effects

Answer 43

* Myalgia * Abdominal pain * Increased ALT/AST (mild) * Rhabdomyolysis (can also be mildly increased CK)

Question 44

high potassium drugs

Answer 44

* ACEi, ARB, spiro/eplerenone/amiloride * Heparin and LMWH * Tolvaptam * Co-trimoxazole

Question 45

# 6 low potassium drugs

Answer 45

Diuretics IV Antifungals (esp. amphotericin) Cisplatin steriods Beta2-agonists gentamicin

Question 46

low magnesium

Answer 46

* Thiazide / thiazide-like diuretics * Loop diuretics * Proton pump inhibitors (usually within 1st year of treatment) * Exchange resins (e.g. calcium resonium) * Ciclosporin * IV bisphosphonates (e.g. during treatment of hypercalcaemia) * IV Antifungals * IV Aminoglycosides

Question 47

drugs that can raise blood sugar or worsen diabetic control

Answer 47

* Steroids * Antipsychotic drugs * Thiazide and thiazide-like diuretics * (Loop diuretics less likely) * Beta-blockers * Tacrolimus

Question 48

4 drugs increasing risk of osteoporosis

Answer 48

Steroids ppi goserelin rarer causes ( methotrexate)