passmed prescription questions Flashcards
oesphagitis tx drug of choice
PPI
ompezaole 40
lanso - 30
Endoscopically proven oesophagitis
mx and tx duration
full dose proton pump inhibitor (PPI) for 1-2 months
if response then low dose treatment as required
if no response then double-dose PPI for 1 month
Endoscopically negative reflux disease duration
full dose PPI for 1 month
what drug to we give to reduce frequency of angina attackd
verapamol or bB
diltizaem ,
when are stimualnt laxatives best taken
ON - once nightly
what receptors does loperamide act on
Loperamide acts on the mu (μ)-opioid receptor expressed on the circular and longitudinal intestinal muscle.
2 se of ccbs
headache
ankle swell
Both oral and topical isotretinoin are strongly contraindicated in pregnancy.
true
is HRT allowed in ischaemic heart disease
no
most approprite info to tell people about tamoxifen
hot flsuhes
increased risk of blood clots
endometrial cancer
following removal of a tumour how long is tamoxifen used for
Tamoxifen is typically used for 5 years following removal of the tumour.
alternatvie to tamoxifen that carriers lower risk of endoemtrial cancer
Raloxifene is a pure oestrogen receptor antagonist, and carries a lower risk of endometrial cancer
what drugs are almost always safe in renal disease - wred
antibiotics: erythromycin, rifampicin
diazepam
warfarin
if trough levels are raised on gent what do you do
The interval between the doses should be increased if the trough levels are raised. ( for examples TDS to BD at the same dose)
if the peak level is too high at gentamicin dose what should you do
reduce the dose of gentamicin but still keeping the frequency the same
As the peak level is too high the dose should be reduced.
for gentamicin what condition has different levels of trough and peak requiremnts
The BNF recommends different target gentamicin concentrations for patients with infective endocarditis (peak 3-5mg/litre, trough < 1mg/litre).
what type of people are more at risk of asthma bronchospams when taking NSAID
Around 10-20% of patients with asthma experience bronchospasm / worsening of asthma control after ingesting NSAIDs.
The risk is increased in patients with nasal polyps and also those who are middle-aged.
can benzos act as resp suppressants
yes
how long is acetylcysteine infused over
Acetylcysteine is now infused over 1 hour (rather than the previous 15 minutes) to reduce the number of adverse effects.
Acetylcysteine commonly causes an anaphylactoid reaction (non-IgE mediated mast cell release). Anaphylactoid reactions to IV acetylcysteine are generally treated by
stopping the infusion, then restarting at a slower rate.
when assessing for digoxin toxicity what are the most importantn values
ECG and U&E
liver transplantation criteria for paracetamol overdose
Arterial pH < 7.3, 24 hours after ingestion
or all of the following:
prothrombin time > 100 seconds
creatinine > 300 µmol/l
grade III or IV encephalopathy
