Session 6: Side Effects — Anxiety & Depression

Question 1

Cardiac arrythmia, hypotension, sedation,
sexual dysfunction, lowers seizure threshold, high incidence of anticholinergic effects (especially in the elderly).

Answer 1

Tricyclic Antidepressants

Question 2

Serotonin syndrome, rash, seizures, increased bleeding when mixed with drugs that affect coagulation, ↓ appetite/wt. loss, hyponatremia, milder anticholinergic effects, ↓ libido, and insomnia

Answer 2

Selective Serotonin Reuptake Inhibitors (SSRIs)

Question 3

Serotonin syndrome, sustained ↑ in BP and
cholesterol, insomnia, somnolence, ↓ appetite/wt. loss, hyponatremia, milder anticholinergic effects, increased bleeding when mixed with drugs that affect coagulation.

Answer 3

Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)

Question 4

Serotonin syndrome, mania, orthostatic hypotension esp. in the elderly, abuse and dependence risks, withdrawal effects can last weeks, hepatotoxicity, seizures, hypoglycemia in diabetics.

Answer 4

Monoamine Oxidase Inhibitors (MAOIs)