Serous Fluid Flashcards
__________ line the membranes
Mesothelial cells
Three closed body cavities
Pleural, pericardial, peritoneal
Serous fluid is normally produced and reabsorbed at a constant rate; disruption of this process produces __________
Effusion
Effusions caused by systemic disorders are
Transudates
Effusions caused by membrane disorders are
Exudates
Pleural fluid collected by
Thoracentesis
Milky pleural fluid
Thoracic duct leakage (chylous effusion), Chronic infection (pseudochylous effusion)
Bloody pleural fluid
Hemothorax, Hemorrhagic effusion (embolus, tuberculosis, malignancy)
Viscous pleural fluid
Malignant mesothelioma producing hyaluronic acid
Neutrophils in pleural fluid
Pneumonia, pancreatitis
Lymphocytes in pleural fluid
Tuberculosis, viral infection
Eosinophils in pleural fluid
Pneumothorax
Mesothelial cells in pleural fluid
Normal, decreased with tuberculosis
Plasma cells in pleural fluid
Tuberculosis
Malignant cells in pleural fluid
Small cell and adenocarcinoma,
Metastatic carcinoma cells
Pleural fluid: pH less than 7.0 indicates
Need for chest tube drainage
Pleural fluid: pH less than 6.0 indicates
Esophageal rupture
Pleural fluid cholesterol
Equal to or less than 45 to 60 mg/dL (transudate),
Higher (exudate)
Pleural fluid: serum cholesterol ratio
Less than 0.3 - transudate
Higher - exudate
Pleural fluid : serum bilirubin ratio
Less than 0.6 - transudate
Higher - exudate
Pericardial fluid collected by
Pericardiocentesis
Cloudy, blood-streaked pericardial fluid
Infection, malignancy
Grossly bloody pericardial fluid
Cardiac puncture,
Anticoagulant medications
Increased neutrophils in pericardial fluid is seen in
Bacterial endocarditis
Peritoneal fluid is often called __________, effusion is _________
Ascitic fluid; ascites
Effusions of peritoneal fluid are caused by
Liver disorders (cirrhosis), Intestinal infection (peritonitis), Malignancy
Serous fluid is located between the ________ and _________ that line the closed body cavities.
Parietal and visceral membranes
Serum-ascites albumin gradient
- 1 or higher is a transudate.
1. 1 or lower is an exudate.
Turbid peritoneal fluid
Infection
Green peritoneal fluid
Gallbladder or pancreas disorder
Blood-streaked peritoneal fluid
Trauma, infection, malignancy
Milky peritoneal fluid
Lymphatic trauma or blockage
Normal WBC count of peritoneal fluid
Less than 350/uL
_____________ distinguishes between cirrhosis and peritonitis.
Absolute neutrophil count.
More than 250 neutrophil/uL or 50% of the differential indicates peritonitis
Additional cells seen in peritoneal fluid include
Abundant mesothelial cells, Lipophages, Yeast, Toxoplasma gondii, Malignant colon, prostate, and ovarian cells.
Peritoneal fluid glucose
Decreased in infection and malignancy
Peritoneal fluid amylase
Elevated in pancreatitis and gastrointestinal perforations
Peritoneal f
Uid alkaline phosphatase
Elevated in intestinal perforation
Peritoneal fluid BUN and creatinine
Bladder rupture and puncture
Peritoneal fluid tumor markers
Carcinoembryonic antigen and CA 125
Microbiology test done on pleural fluid
Acid fast stains
Pericardial fluid: refer metastatic malignant cells for____________
Cytologic examination
Pericardial fluid: gram stains and cultures are performed on ___________
Concentrated specimens
Pericardial fluid: acid-fast stains for tuberculosis are associated with_____________
Acquired immunodeficiency syndrome
Recommended method for differentiating peritoneal fluid
Serum-ascites albumin gradient