Serotonin Syndrome Flashcards
1
Q
what can cause serotonin syndrome?
A
- monoamine oxidase inhibitors
- SSRIs
- ecstasy
- amphetamines
2
Q
what medications interact with SSRIs and increase the likelihood of developing serotonin syndrome?
A
- st johns wort
- tramadol
3
Q
what are the neuromuscular features of serotonin syndrome?
A
excitation
* hyperreflexia
* myoclonus
* rigidity
4
Q
what are the autonomic nervous system features of serotonin syndrome?
A
excitation
* hyperthermia
* sweating
5
Q
what mental state features are seen in serotonin syndrome?
A
confusion
6
Q
how is serotonin syndrome managed?
A
- supportive including IV fluids
- benzodiazepine
- severe = serotonin antagonists
7
Q
name serotonin antagonists
A
- cyproheptadine
- chlorpromazine
8
Q
what clinical signs can be seen in serotonin syndrome?
A
- tachycardia
- raised BP
- hyperreflexia
- clonus
- dilated pupils
- pyrexia
