Monoamine Oxidase Inhibitors Flashcards

1
Q

what is the role of monoamine oxidase?

A

metabolises serotonin and noradrenaline in the presynaptic cell

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2
Q

name some examples of non-selective monoamine oxidase inhibitors

A
  • tranylcypromine
  • phenelzine
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3
Q

when are non-selective monoamine oxidase inhibtors used?

A

atypical depression

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4
Q

what are the adverse-effects of non-selective monoamine oxidase inhibitors?

A
  • hypertensive reactions to tyramine containing foods
  • anticholinergic effects
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5
Q

what foods contain tyramine?

A
  • cheese
  • pickled herring
  • bovril
  • oxo
  • marmite
  • broad beans
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