Seronegative arthritis - TABLE

Question 1

Features spondyloarthropathies have in common - see table

Answer 1

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Question 2

Characteristic pattern of joint involvement in spondyloarthropathies compared with other arthropathies - see table

Answer 2

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Question 3

Characteristic features of each spondyalrthopathy - see table

Answer 3

.

Question 4

ASAS (Assessment in Ankylosing Spondylitis) classification criteria of ankylosing spondylitis

Answer 4

> 3 months back pain + age onset <45

Sacroilitis on imaging + at least one ankylosing spondylitis symptom/sign
OR
HLA-B27 status + at least 2 ankylosing spondylitis symptoms/signs

Question 5

Features of ankylosing spondylitis according to ASAS (Assessment in Ankylosing Spondylitis) classification

Answer 5

Inflammatory back pain
Arthritis
Enthesitis of heel
Uveitis
Dactylitis
Psoriasis
Crohn's/UC
Good response to NSAIDs
FH of spondyloarthritis/arthropathy
HLA-B27
Elevated CRP

Question 6

Extra-articular features of ankylosing spondylitis

• eyes
• GI
• resp
• cardio
• skin
• renal
• bone

Answer 6

Eyes - uveitis

GI - IBD

Resp - restrictive lung disease, apical fibrosis

Cardiac - aortic regurgitation, heart block

Skin - psoriasis

Bone - osteoporosis and spinal fractures

Renal - secondary amyloidosis