sepsis Flashcards
1
Q
what is sepsis
A
a condition where the body launches a large immune response to an infection that causes systemic inflammation and affects bodily organ functioning
2
Q
septic shock
A
arterial BP drops and results in organ hyperfusion
leads to rise in lactate as organs begin anaerobic respirtation
3
Q
how can septic shock be measurs
A
systolic BP <90 despite fluid resuscitation
lactate >4mmol/l
4
Q
septic shock initial management
A
IV fluids
If IV fluids don’t give improvement escalate to high dependency where inotropes can be used
5
Q
severe sepsis
A
sepsis is present and results in organ dysfunction
- hypoxia
- oliguria
- AKI
- thrombocytopenia
- coagulation dyfunction
- hypotension
- lactate >2
6
Q
risk factors
A
young or old age chronic conditions - COPD, diabetes chemotherapy immunosuppresion, steroids surgery recent trauma, burn pregnancy indweling medical device e.g. catheters
7
Q
Ix
A
FBC U&Es LFTs CRP clotting blood cultures blood gas
8
Q
Sepsis 6
A
3 tests:
- lactate
- blood cultures
- urine output
3 treatments
- O2
- empirical broad spectrum antibx
- IV fluids
9
Q
neutropenic sepsis
A
sepsis in patient with low neutrophil acount of less than 1
10
Q
neutropenic sepsis antibx
A
piperacillin with tazocin
