Section 4

Question 1

What are protein domains?

Answer 1

Small sections that cofactors bind to

Question 2

What is NAD+?

Answer 2

Niacin (Vit. B3)

Question 3

What reaction is catalyzed by lactate dehydrogenase?

Answer 3

Lactate -> Pyruvate -> Repeat

Question 4

What is a hexokinase?

Answer 4

Enzyme that phosphorylates glucose

Question 5

Where do hydrophobic amino acids tend to be at?

Answer 5

Interior of a protein

Question 6

What is a ligand-binding domain?

Answer 6

Responsible for hormone binding

Question 7

What is a G protein?

Answer 7

Binds to GDP or GTP

Question 8

What is the function of myoglobin?

Answer 8

Brings oxygen to heart and skeletal muscles

Question 9

What is the function of hemoglobin

Answer 9

Brings oxygen to tissues via RBC

Question 10

Which have a higher saturation w/ oxygen, hemoglobin or myoglobin?

Answer 10

Myoglobin (due to its quaternary structure)

Question 11

What is the function of heme?

Answer 11

Bind to oxygen

Question 12

What is bilirubin?

Answer 12

Degraded hemoglobin that is excreted in bile

Question 13

What is conjugated bilirubin?

Answer 13

When sugar attaches to unconjugated bilirubin that is formed in the liver

Question 14

What does a point mutation involve?

Answer 14

A replacement of hemoglobin glutamic residue with a valine residue

Question 15

What is the result of a point mutation?

Answer 15

Sickled red blood cells

Question 16

Which sequence determines protein folding? Which physically folds?

Answer 16

Primary,

Tertiary

Question 17

What are chaperonins?

Answer 17

Acts as a template to overcome the kinetic/thermodynamic barrier to reaching a stable conformation

Question 18

Which AA is known as a helix breaker?

Answer 18

Proline