Section 1 Flashcards

1
Q

During the fed state, what does Acetyl-CoA turn to in the liver?

A

TCA for ATP or as a triglyceride

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2
Q

During the fed state, what d TG bring from the liver?

A

Turns to VLDL then Glycerol

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3
Q

During the fed state, glucose from the intestines go where?

A

Liver, Brain, RBC, Muscle, Adipose tissue

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4
Q

What are the three main ketone bodies?

A

Acetone, acetoacetone, and beta-hydroxybutrate

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5
Q

What would be an example of a xenobiotic?

A

Any drug

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6
Q

During the fed state, where do fatty acids come from?

A

Chylomicrons from the intestines

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7
Q

During the starved state, where do ketone bodies go to?

A

Brain

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8
Q

During the fasting state, where does the FA from the adipose tissue go to?

A

Muscle + Liver

Muscle: used for Acetyl-CoA, then TCA, then ATP

Liver: same as muscle and be used to form Acetyl-CoA, the Ketone bodies

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9
Q

During the fasting state, how does the liver get its glucose?

A
  1. Glycogen storage from the liver breaks down to glucose
  2. Adipose tissue breaks down TG to Glycerol then to glucose in the liver
  3. Muscle can break down its glycogen storage or break down its proteins and use up its AA
  4. RBC can break down Lactate to form Glucose in the liver
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10
Q

Where are chylomicrons derived from during the fed state?

A

Fats from the duodenum

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11
Q

During the fasting state, where does the glucose from the liver go to?

A

Brain + RBC

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12
Q

During the fasting state, what does TG in the Adipose tissue break down to?

A

Glycerol + FA

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13
Q

What is the resting metabolic rate?

A

24kcal/kg/day

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14
Q

Vit. A deficiency symptom

A

Xerophthalmia

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15
Q

During the fasting state, where do ketone bodies go to?

A

Muscles; helps make Acetyl-CoA, then more ATP

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16
Q

During the fed state, what does glucose break down to in the muscle?

A

Either Acetyl-CoA then to ATP or stored as glycogen

17
Q

What is the difference between starch and glycogen?

A

Glycogen has more branches

18
Q

What determines whether a specific amino acid is essential?

A

If we cant make them

19
Q

During the fed state, what are the two pathways glucose can go to in the liver?

A

Store as glycogen or break down to Acetyl-Coa

20
Q

Vit. K deficiency symptoms

A

Defective blood coagulation

21
Q

As you slowly starve, what levels increase / decrease

A

Glucose levels go down, FA go up, but dont surpass glucose. After 7 days, ketone bodies will skyrocket and surpasss glucose levels.

22
Q

Vit. D deficiency symptoms

A

Rickets

23
Q

What two organs store glucose as glycogen?

A

Liver + Muscle

24
Q

Vit. E deficiency symptoms

A

Muscular dystrophy, neurologic abnormalities

25
Q

During the fed state, where does the liver get its glucose from?

A

Intestines

26
Q

How would you calculate basal metabolic rate for a sedimentary person

A

24kcal/kg/day + 30%

27
Q

During the starved state, what is not available?

A

Proteins in the muscles, glucose to the brain from the liver, urea is not being produced from the liver to kidney

28
Q

During the fed state, what does glucose break down to in the brain?

A

Acetyl-Coa then ATP

29
Q

During the fed state, what two ingredients are needed to make TG in the adipose tissue?

A

FA from the chlylomicrons + Glycerol from the VLDL of the liver

30
Q

During the fed state, what does glucose break down to in the RBC?

A

Pyruvate then Lactate

31
Q

What three regions can glucose enter without the need of insulin?

A

Kidney, eyes, and feet