SDL: Respiratory Disease in Adult Cattle Flashcards

1
Q

What is fog fever and what toxin causes it?

A
  • Atypical form of interstitial pneumonia.
  • Ingestion of large quantities of L-tryptophan
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2
Q

What types/ages of cattle is fog fever generally seen in?

A
  • Cattle over two years old
  • More common in suckler herds
  • Common in cattle that have previously been on little nutrition and are then put on more lush pasture in autumn (September to November)
  • Normally seen within two weeks of entry to new pasture
  • Hereford and Hereford crosses seem particularly susceptible
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3
Q

How does ingestion of large quantities of L-tryptophan cause disease?

A
  • L-tryptophan in grass is metabolised in the rumen to indole acetic acid (IAA)
  • IAA decarboxylated by Lactobacillus spp. to produce 3-methyl indole (3MI)
  • 3MI causes destruction of the pulmonary cells e.g. type I pneumonocytes and monociliated bronchiolar secretory cells resulting in pathological changes
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4
Q

What clinical signs do cattle with fog fever show if severely affected?

A
  • Sudden onset dyspnoea
  • Loud respiratory grunt
  • Mouth breathing
  • Frothing at the mouth
  • Auscultation often reveals little, soft, moist sounds, occasionally crackles
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5
Q

What clinical signs do cattle with fog fever show if not severely affected?

A
  • Tachypnoea (50-80 per minute)
  • Hypernoea
  • No dyspnoea
  • Auscultation less severely effected: harsh sounds
  • Normal rectal temperature
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6
Q

How would you diagnose fog fever?

A
  • Necropsy findings (haemorrage, pulmonary oedema, erythema of the lungs etc.)
  • Histological examination (Severe congestion and oedema of pulmonary tissue)
  • History
  • Clinical signs
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7
Q

What other differentials would you have alongside fog fever?

A
  • Husk
  • Pneumonic pasteurellosis
  • Nitrate poisoning
  • IBR
  • Thrombosis of caudal vena cava
  • Brassica poisoning
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8
Q

How would you treat fog fever?

A
  • Remove cattle from incriminated pasture
  • Treatment tends to be empirical (supportive)
  • Atropine 1g per 450kg BW IV acts as a bronchodilator
  • Corticosteroids can be beneficial
  • Flunixin meglumine can be beneficial in acute pulmonary emphysema
  • Reduce stress
    • Movement and unnecessary stressing of affected individuals at this point can cause animals to drop dead
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9
Q

How would you prevent fog fever?

A
  • Restrict grazing for short periods during the first two weeks
    • 2 hours on the first day then increasing by an hour a day
  • Strip graze/graze with sheep prior to putting cattle on pasture
  • Monesin sodium 200mg/head/day before and after entering the pasture
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10
Q

When does infectious bovine rhinotracheitis tend to occur?

A
  • Condition can occur in animals at grass but is much more severe when a group of housed animals are affected.
  • Introduction of infection to a group of cattle is usually via a carrier or animal incubating the disease.
  • Can occur after purchase of animals, or if off the farm on agricultural shows etc.
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11
Q

What are the clinical signs of IBR?

A
  • Dullness
  • Reduced appetite
  • Pyrexia
  • Profuse nasal and ocular discharges
  • Frequent coughing.
  • In severe cases, finding necrotic plaques on nasal mucosa.
  • Auscultation of the chest may reveal loud lung noises, but often difficult to interpret.
  • Reduced milk yield and abortion may also occur.
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12
Q

What is atopic rhinitis?

A
  • Upper respiratory tract disorder of grazing cattle.
  • Can be confused with IBR.
  • Highly seasonal – seen at start of grazing period. Caused by allergy to inhaled antigens such as pollens
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13
Q

What are the clinical signs of atopic rhinitis?

A
  • Ocular and nasal serous discharge
  • Nasal pruritis
  • Sneezing.
  • This progresses over several weeks to:
    • Mucopurulent discharge
    • Swelling of nasal mucosa
    • Ulceration of nasal mucosa with bleeding and white nodules up the nostrils.
  • Does not spread to other cattle like IBR does – helps to differentiate the two diseases.
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14
Q

What is Farmers lung?

A
  • Extrinsic allergic alveolitis
  • Inhalation of spores and metabolic products of Micropolyspora faenia produce a type III hypersensitivity at the level of the alveoli
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15
Q

When is farmers lung generally seen?

A
  • Seen in cattle who have been fed hay that has been baled at too high moisture content
    • Metabolism of saprophytic microflora causes overheating and consequently M. faeni proliferates
  • More common in West of UK
  • Commonly occurs during winter when feeding conserved fodder
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16
Q

What are the clinical signs of acute farmers lung cases?

A
  • Respiratory signs
    • Hyperpnoea
    • Occasionally dyspnoea with mouth breathing
    • Crackles on auscultation in cranioventral lung fields in some cases
  • Other clinical signs
    • Complete agalactica
    • Occasionally pyrexia
    • Bright demeanour
17
Q

What are the clinical signs of chronic farmers lung cases?

A
  • Respiratory signs
    • Chronic coughing over several housing periods with remission when turned out on grass
    • Coughing, produces copious amounts of green discharge
    • Hyperpnoea
    • Tachypnoea
    • Crackles and squeaks over anteroventral lung fields
  • Other clinical signs
    • Insidious weight loss
    • Weight loss
    • Reduced milk yield
18
Q

What history do cases of acute bacterial pneumonia generally present with?

A
  • Individual animal affected
  • Animals may have history of transport which has caused chronic suppurative pulmonary disease which has been exacerbated to present as acute disease.
  • History of bad drenching technique or regurgitation in a weak cow can result in inhalation pneumonia which will present the same.
19
Q

What are the clinical signs of acute bacterial pneumonia?

A
  • Sudden onset pyrexia
  • Dullness
  • Tachypnoea
  • Coughing
  • Anorexia
  • Reduced milk production will occur
  • Harsh auscultatory sounds due to tachypnoea
  • Occasionally squeaks may also be heard
20
Q

How is acute bacterial pneumonia diagnosed and treated?

A
  • Diagnosis: Often diagnosed under umbrella terms of pneumonic pasteurellosis or bacterial pneumonia
  • Treatment: Rapid response to antibiotics will be seen
21
Q

How does a milk allergy develop in cattle?

A
  • Hypersensitivity reaction – cow develops allergy to the alpha casein in her own milk
  • Associated with interruption of normal milking routine such as drying off or showing animal
  • More often seen in Channel Island breeds – probably inherited component
22
Q

What are the clinical signs of a milk allergy in cattle?

A
  • Tachypnoea, hyperpnoea (increased effort) in in severe cases dyspnoea.
  • Usually no cough.
  • Auscultation may reveal adventitious sounds, particularly crackles in ventral lung fields
  • Sometimes urticarial skin lesions are seen
  • Clinical signs alleviated by prompt milking
23
Q

What is chronic suppurative pneumonia and when does it usually present?

A
  • Most common chronic pulmonary disorder of individual adult animal
  • More commonly present during housing but may present when at grass
  • Clinical course of disease is normally long.
24
Q

What are the clinical signs of chronic suppurative pneumonia?

A
  • Dullness
  • Weight loss
  • Tachypnoea
  • Coughing
  • Thoracic pain may be seen upon percussion of chest and often causes bout of pained coughing
  • Adventitious lung sounds may or may not be heard. If present are usually restricted to cranioventral lung lobes and tend to be squeaks.
  • Occasionally animals develop nectrotising bronchopneumonia with pleurisy and become markedly duller, pyrexic, exhibit halitosis, severe thoracic pain and die within a few days
25
Q

Posterior vena cava thrombosis with pulmonary embolism occurs sporadically in adult cattle. What are the clinical signs?

A
  • Haemoptysis
  • Thoracic pain (associated with the pulmonary embolism)
  • Pallor of mucus membraes
  • Melaena
  • Audible squeaks on auscultation of the lung fields
  • Hepatomegaly
  • Occasionally ascites if hepatic veins have been blocked by the thrombus
26
Q

What is the usual history of posterior vena cava thrombosis with pulmonary embolism?

A
  • Protracted weight loss
  • Coughing but duration and severity can vary
  • Some have chronic cough
  • Others initial signs if coughing up blood
27
Q

What is diffuse fibrosing alveolitis?

A
  • Chronic condition
  • Older animals
  • Aetiology unclear
  • May be due to an endstage of repeated annual bouts of fog fever or farmers lung
28
Q

What are the clinical signs of diffuse fibrosing alveolitis?

A
  • Prolonged history of:
    • Coughing
    • Weight loss
  • Bright
  • Hyperpnoeic
  • Widespread adventitis sounds over both lung fields
  • May develop clinical signs of congestive heart failure due to cor pulmonale (abnormal enlargement of the right side of heart as a result of disease of the lungs or the pulmonary blood vessels)
29
Q

List differentials for: a group of adult suckler cows at grass which have developed respiratory signs over the last 48 hours.

A
  • Fog fever
  • Reinfection husk
  • Atopic rhinitis
  • IBR
30
Q

List differentials for: a single adult dairy cow which has developed respiratory signs over the last month.

A
  • Acute bacterial pneumonia
  • Milk allergy
  • Posterior vena cava thrombosis with pulmonary embolism
  • Chronic supprative pneumonia
  • Diffuse fibrosis alveolitits
31
Q

List differentials for: a straw yard full of 3-10 month old barley beef bulls which have developed respiratory signs over the last 48 hours.

A
  • Farmers lung
  • Fog fever
  • IBR
  • Aspiration pneumonia
  • Diffuse fibrosis alveolitis
  • Dusty feed rhinotracheitis
  • Other viral respiratory diseases
    • Parainfluenza 3
    • Bovine synccitial virus