sciencey derm Flashcards
what is the function of the keratin layer?
acts as a physical barrier to pathogens
what is the function of karatinocytes?
helps mediate immune response
what are langerhan cells?
dendritic cells interspersed with keratinocytes in the epidermis
what is the function of langerhan cells?
antigen presenting cells characterised by the birbeck granule
which cells are responsible for graft rejection?
MHC cells
what is a pruritoceptive itch?
something (usually inflammation/dryness) in/on the skin triggers itch
what is a neuropathic itch?
damage to central/peripheral nerve
what is a neurogenic itch?
no evident damage to CNS but itch characterised by damage eg opiates effect on CNS
what is a psychogenic itch?
psychological causes with no CNS involvement eg. itch in dillusion
what is a cream?
a semisolid emulsification of oil in water that contains preservatives
what is an ointment?
semisolid grease with high lipid content and no preservatives
what is a lotion?
liquid formation of medications suspended in alcohol/water
what is a gel?
semisolid, thickened aqueous solutions
what is a paste?
semi solid, made up of finely powdered materials
what is a foam?
colloid with 2/3 phases
what do eccrine glands produce?
sweat
what do appocrine glands produce?
body odour
what is responsible for vibration sensation?
meisseners corpuscles
what is responsible for pressure sensation?
Pacinian corpuscles
where are langerhan cells found?
prickle cell layer
where are langerhan cells derived from?
bone marrow
what colour is eumelanin?
brown
what colour is phaeomelanin?
red
where are melanocytes located?
basal cell layer
