sciencey derm Flashcards

1
Q

what is the function of the keratin layer?

A

acts as a physical barrier to pathogens

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2
Q

what is the function of karatinocytes?

A

helps mediate immune response

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3
Q

what are langerhan cells?

A

dendritic cells interspersed with keratinocytes in the epidermis

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4
Q

what is the function of langerhan cells?

A

antigen presenting cells characterised by the birbeck granule

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5
Q

which cells are responsible for graft rejection?

A

MHC cells

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6
Q

what is a pruritoceptive itch?

A

something (usually inflammation/dryness) in/on the skin triggers itch

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7
Q

what is a neuropathic itch?

A

damage to central/peripheral nerve

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8
Q

what is a neurogenic itch?

A

no evident damage to CNS but itch characterised by damage eg opiates effect on CNS

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9
Q

what is a psychogenic itch?

A

psychological causes with no CNS involvement eg. itch in dillusion

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10
Q

what is a cream?

A

a semisolid emulsification of oil in water that contains preservatives

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11
Q

what is an ointment?

A

semisolid grease with high lipid content and no preservatives

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12
Q

what is a lotion?

A

liquid formation of medications suspended in alcohol/water

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13
Q

what is a gel?

A

semisolid, thickened aqueous solutions

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14
Q

what is a paste?

A

semi solid, made up of finely powdered materials

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15
Q

what is a foam?

A

colloid with 2/3 phases

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16
Q

what do eccrine glands produce?

A

sweat

17
Q

what do appocrine glands produce?

A

body odour

18
Q

what is responsible for vibration sensation?

A

meisseners corpuscles

19
Q

what is responsible for pressure sensation?

A

Pacinian corpuscles

20
Q

where are langerhan cells found?

A

prickle cell layer

21
Q

where are langerhan cells derived from?

A

bone marrow

22
Q

what colour is eumelanin?

A

brown

23
Q

what colour is phaeomelanin?

A

red

24
Q

where are melanocytes located?

A

basal cell layer

25
Q

what type of cells are melanocytes?

A

dendritic cells

26
Q

where are melanocytes derived from?

A

neuronal cell crest

27
Q

where is the dermis derived from?

A

mesoderm

28
Q

where is the epidermis derived from?

A

ectoderm

29
Q

what kind of epithelium is the epidermis?

A

stratified squamous epithelium