Derm Flashcards

1
Q

what is hyperkeratosis?

A

increased thickness in the keratin layer

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2
Q

what is parakeratosis?

A

persistence of nuclei in the keratin layer

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3
Q

what is acathosis?

A

increased thickness of epithelium

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4
Q

what is papillomatosis?

A

irregular epithelial thickening

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5
Q

what is spongiosis?

A

oedemal fluid between sqames appears to increase prominence of intercellular prickles

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6
Q

what is a macule?

A

a flat colour change <1cm

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7
Q

what is a patch?

A

a flat colour change >1cm

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8
Q

what is a papule?

A

localised elevated area <0.5cm

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9
Q

what is a nodule?

A

localised elevated area >0.5cm

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10
Q

what is a pustule?

A

pus filled spot

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11
Q

what is a vesicle?

A

fluid filled <0.5cm

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12
Q

what is a bulla?

A

fluid filled >0.5cm

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13
Q

what is a plaque?

A

raised edge with flatter surface >0.5cm

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14
Q

what is a wheal?

A

a compressible dermal swelling

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15
Q

what is a cyst?

A

a nodule containing semisolid material

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16
Q

what is purpura?

A

extravasation of blood, will not blanche, may be raised

17
Q

what is a scale?

A

accumulated fragments of keratin layer

18
Q

what is a crust?

A

dried exudate

19
Q

what does lichenified mean?

A

thickening with increased skin markings

20
Q

what is an erosion?

A

a superficial break in the dermis

21
Q

what is an ulcer?

A

a deeper break into the dermis

22
Q

what is a scar?

A

normal tissue replaced by fibrous tissue

23
Q

what is atrophy?

A

loss of epidermis +/- dermis

24
Q

how is scabies treated?

A

permethrin

25
Q

how is eczema herpeticum treated?

A

aciclovir

26
Q

how is ramsey-hunt syndrome treated?

A

oral aciclovir and oral corticosteroids

27
Q

what is first line treatment of chronic plaque psoriasis?

A

Topical potent corticosteroid + vitamin D analogue

28
Q

what may be necessary in severe urticaria?

A

A short course of an oral corticosteroid may required in addition to a non-sedating antihistamine

29
Q

what is seen under immunofluorescence in bullous pemphigoid?

A

IgG and complement deposition around the dermoepidermal junction

30
Q

what causes porphyria cutanea tarda?

A

an inherited defect in uroporphyrinogen decarboxylase