GI Flashcards

1
Q

what are the symptoms of biliary colic?

A

colicky abdo pain, worse after eating (particularly fatty meals)

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2
Q

what is the management of biliary colic?

A

a laparoscopic cholecystectomy

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3
Q

what are the symptoms of acute cholecystitis?

A

RUQ pain
fever
murphys sign positive (pain on inspiration with pressure on the costal margin)
?mildly deranged LFTs

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4
Q

how is acute cholecystitis treated?

A

USS and cholecystectomy within 48hrs of presentation

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5
Q

what are the symptoms of cholangitis?

A

patient severely unwell and septic
jaundice
RUQ pain

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6
Q

how is cholangitis treated?

A

fluid resuscitation and broad spec IV abx

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7
Q

what are the symptoms of primary biliary cholangitis?

A

usually seen in middle aged females
thought to be autoimmune
sjogrens association
jaundice
pruritic

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8
Q

what antibodies are present in PBC?

A

anti mitochondrial antibodies

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9
Q

how is PBC treated?

A

USS required for diagnosis
ursodeoxycholic acid
cholesystamine for itch

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10
Q

what is primary sclerosing cholangitis?

A

biliary disease of unknown cause characterised by inflammation
associated with UC

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11
Q

what are the symptoms of PSC?

A

jaundice
pruritic
increased bilirubin and ALP levels
RUQ pain

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12
Q

what is the management of PSC?

A

ECRP/MCRP

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13
Q

what does PSC increase the risk of?

A

colorectal cancer and cholangiocarcinoma

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14
Q

what is used first line in ascites?

A

aldosterone antagonists- spironolactone

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15
Q

what is the definition of Barrett’s oesophagus?

A

Replacement of stratified squamous epithelium -> columnar epithelium [metaplastic change]

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16
Q

where is oesophageal cancer most likely to occur?

A

Lower 1/3 of oesophagus

Reflux insult is greatest here

17
Q

what is first line for C diff?

A

Oral vancomycin is the first line antibiotic for use in patients with C. difficile infection