Schizophrenia- Movement Disorders and Treatments Flashcards

1
Q

Acute dystonia description and symptoms

A

Painful prolonged muscle contractions
Involuntary buccal, facial, oculogyric
May involve back, arms, and legs

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2
Q

Onset of acute dystonias

A

24-96 hours after dose change or drug started

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3
Q

High risk APs for acute dystonias

A

High potency or high dose FGA
Younger men

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4
Q

Acute dystonias treatment

A

anticholinergics, IM benzos, decrease dose or D/C

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5
Q

Pseuoparkinsonism description and symptoms

A

Bradykinesia
Tremor
Pill rolling
Cogwheel rigidity
Postural and oral abnormalities
Akinesia
Difficulty initiating movement
Slowness
Masked facial expression
Micrographia
Slowed speech
Decreased arm swing

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6
Q

Onset of pseudoparkinsonism

A

1-2 weeks after dose change or drug started

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7
Q

High-risk APs for pseudoparkinsonism

A

High potency or high dose FGA
Older age
Females

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8
Q

Pseudoparkinsonism treatment

A

Anticholinergics
Decrease dose or D/C

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9
Q

Akathisia description and symptoms

A

Restlessness, pacing, shuffling, compulsion to stay in motion, subjective feelings of distress

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10
Q

Akathisia onset

A

hours-days after start or dose change

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11
Q

High-risk APs for akathisia

A

High potency FGAs, aripiprazole, risperidone

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12
Q

Akathisia treatment

A

Beta-blockers, decrease dose or D/C

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13
Q

Tardive dyskinesia description and symptoms

A

Tongue thrusting, chewing, lip smacking, grimacing, limb twisting, rocking

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14
Q

Onset of tardive dyskinesia

A

Months-years after initiation, can be irreversible

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15
Q

Treatment of tardive dyskinesia

A

Prevention, D/C med

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16
Q

Anticholinergics can do what to tardive dyskinesia?

A

Mask the symptoms

17
Q

EPS treatment options

A

Diphenhydramine
Benztropine
Trihexyphenidyl
Biperiden
Amantadine
Propranolol, nadolol, metoprolol (AKATHSIA ONLY)
PO/IM benzos (lorazepam, diazepam, clonazepam)