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Psychiatry > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

Familial prevalences for schizophrenia

A

Prevalence of schizophrenia in:

General population: 1%

Non-twin sibling of schizophrenia patient: 8%

Child with one parent with schizophrenia: 12%

Dizygotic twin of a schizophrenia patient: 12%

Child with two parents with schizophrenia: 40%

Monozygotic twin of a schizophrenia patient: 47%

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2
Q

Definition of late onset schizophrenia

A

Onset > 45

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3
Q

Prognostic significance of mood symptoms in schizophrenia

A

Good prognostic indicator

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4
Q

The commonest cause of early mortality in schizophrenia

A

Cardiovascular

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5
Q

Thinking a stranger is someone you know

A

Fregoli delusion

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6
Q

The prevalence of schizophrenia is roughly equal in men and women T/F

A

T

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7
Q

What has the CPA set as an acceptable waiting time for assessment in non-urgent first episode of psychosis referrals? #CanMed

A

Two weeks

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8
Q

Neurocognitive testing is a robust predictor of functioning in first episode psychosis and should be undertaken at initial assessment T/F #CanMed

A

T

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9
Q

What proportion of individuals with q2211.2 deletion have schizophrenia? #CanMed

A

25%

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10
Q

What is the lifetime risk for suicide in schizophrenia? #CanMed

A

Around 5%

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11
Q

Antipsychotic therapy reduces the risk of violence and crime in individuals with schizophrenia T/F #CanMed

A

T

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12
Q

Psychotic symptoms like persecutory delusions are associated with violence in schizophrenia T/F #Canmed

A

T

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13
Q

When should you change antipsychotic if there is no response in first episode? #CanMed

A

Four weeks

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14
Q

For how long should treatment with antipsychotics be continued after resolution of positive symptoms in FEP? #CanMed

A

18 months

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15
Q

How do CanMed define an adequate trial of clozapine?

A

At least 8 but preferably 12 weeks of Rx at 400mg/d with trough levels over 350ng/ml for once day dosing or 250ng/ml for twice day

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16
Q

What proportion of individuals with schizophrenia meet criteria for TRS? #CanMed

A

25-30%

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17
Q

Treatment of choice for schizophrenia with aggression #CanMed

A

Clozapine

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18
Q

According to CanMed what is the minimum effective dose of family intervention in schizophrenia for individuals in close contact w family members?

A

Ten sessions over a three month period

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19
Q

According to CanMed what should be offered to all patients who have not adequately responded to antipsychotic medication?

A

CBT for psychosis

20
Q

Lifetime prevalence of delusional disorder

A

0.2% DSM V

21
Q

Delusional disorder may be more prevalent in older individuals T/F

A

T DSM V

22
Q

Duration of episode of disturbance in brief psychotic disorder in DSM V

A

At least 1 day but less than 1 month

23
Q

Two of which 5 criteria for a schizophrenia diagnosis in DSM V

A
  1. Delusions
  2. Hallucinations
  3. Disorganised speech
  4. Grossly disorganised or catatonic behaviour
  5. Negative symptoms
24
Q

Length of duration of symptoms for a diagnosis of delusional disorder in DSM V

A

One month

25
Q

According to K&S what characterizes the delusions of delusional disorder?

A

They are non-bizarre, ie about potentially normal scenarios like being in love, being followed etc. In contract to delusions in schizophrenia which are more likely to be bizarre

26
Q

Mean age of onset in delusional disorder

A

About 40

27
Q

There is a slight preponderance of female pts in delusional disorder T/F

A

T (K&S)

28
Q

Schizophrenia in elderly ppl respond poorly to medication T/F

A

F (K&S)

29
Q

Lifetime prevalence of schizoaffective disorder

A

0.5-0.8%

30
Q

Which schizoaffective ppl do better, affective or psychotic predominant?

A

Affective

31
Q

Mood and psychotic symptoms have to co-exist for how long for a diagnosis of schizoaffective disorder in DSM V?

A

2/52

32
Q

The most important risk factor for suicide in schizophrenia

A

MDE (K&S)

33
Q

What percentage of pts with post-partum psychosis have a family psychiatric history (& what is it of?)

A

50% fam hx of mood disorders

34
Q

Rate of postpartum psychosis

A

1-2/1000 births

35
Q

When does postpartum psychosis arise?

A

Always within 8 wks of delivery, mean onset is after 2-3 weeks, can occur after a few days

36
Q

In late onset schizophrenia symptoms become less marked as the pt ages T/F

A

T (K&S)

37
Q

Command hallucinations are a risk factor for suicide in schizophrenia T/F

A

T

38
Q

By definition ppl with delusional disorder do not have prominent or sustained hallucinations T/F

A

T (K&S). But they might rarely have auditory

39
Q

Most common types of delusion in delusional disorder (2)

A

Persecutory and jealous-type (K&S)

40
Q

Morbid jealousy in schizophrenia- women predominate T/F

A

T

41
Q

Othello syndrome men predominate T/F

A

T

42
Q

What characterizes de clerambault syndrome (erotomania)?

A

The delusional conviction that another person, usually of higher status, is in love with him or her. Often has a sudden onset. Object of a higher rank, and is the first to fall in love, and is the first to make advances. Pt rationalises paradoxical behaviour of object. Hallucinations are absent. Can occur with schizophrenia, mood disorders, or organic pathology

43
Q

Men with erotomania predominate in forensic populations and women in community samples T/F

A

T

44
Q

Insidious onset is typical in delusional disorder T/F

A

F, it’s usually sudden onset according to K&S

45
Q

Good prognostic factors in delusional disorder

A
  1. Being female
  2. Good premorbid functioning
  3. Onset before age 30
  4. Sudden onset
  5. Short duration of illness
  6. Presence of precipitating factors
46
Q

Time cutoffs for brief psychotic disorder

A

One day to one month

Psychiatry (27 decks)

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