Salmonella

Question 1

What does Salmonella bongori infect

Answer 1

Reptiles/cold-blooded

Question 2

What does Salmonella enterica infect

Answer 2

Warm blooded vertebrates

Question 3

Salmonella difference from E.coli

Answer 3

Doesn’t ferment lactose but grows on MacConkey plates- straw yellow colonies

Question 4

Antigens for serotyping salmonella

Answer 4

K- capsule
O-lipopolysaccharide
H-flagella

Question 5

What is the genetic basis for virulence of salmonella

Answer 5

Pathogenicity islands

Question 6

What is SPI 1

Answer 6

Encodes the type 3 secretion system with the needle for injecting proteins into host cells

Question 7

Salmonella Pathogenesis

Answer 7

Attach and adhere with fimbriae

Some invade cells

Question 8

What are the 2 types of salmonellosis (based on target cells) and diseases they cause

Answer 8

M cells, which cause enteric fever and enterocytes, which cause gastroenteritis

Question 9

What is enteric fever and what does it cause

Answer 9

Infection of lymphoid tissue where bacteria survive and replicate in macrophages and can spread all over the body (liver, spleen) which causes typhoid fever, pullorum disease, Dublin in cattle, Abortis- ovis in sheep and goats, septicemia, fever, swollen lymph nodes

Question 10

What is Gastroenteritis caused by salmonella

Answer 10

Invading the enterocytes through the tight junctions of the intestinal mucosa causing inflammation which causes fluid secretion as a host response resulting in vomiting and diarrhea

Question 11

Predisposing conditions for salmonella

Answer 11

Young/old/immunocompromised/shipping stress/birthing
Parasites or viral infections 
Poor sanitation
Overcrowding  
Over- training