Fusobacterium and Dichelobacter Flashcards
Fusobacterium necrophorum staining characteristics and characteristics
Gram negative anaerobic (aerotolerant) rods
Fusobacterium necrophorum found where
Normal flora of mouth, pharynx, rumen, and intestinal tract and urogenital tract of animals and found in environment with feces
Fusobacterium necrophorum pathogenic features
Leukotoxin that kills neutrophils, macrophages, and hepatocytes
Fusobacterium necrophorum Transmission
Endogenous spread from oral mucosa or G.I. Tract or exogenous from manure in enviornment
Fusobacterium necrophorum Pathogenesis
Invades and multiplies in anaerobic enviornment (damaged tissues lacking proper blood flow) or secondary because of feces contamination
Fusobacterium necrophorum Disease in respiratory system is? What does it do and what does it infect
Calf diphtheria aka necrotic laryngitis or laryngeal necrobacillosis causing cough and fever and bad breath. Can be secondary invader after viral infection. Often affects cows in feed lots
Fusobacterium necrophorum Disease in liver is?
Necrobacillosis of the Liver- causes liver assesses in ruminants usually is a secondary infection of the naval in neonates or from increased feeding of grain—> rapid fermentation in the rumen—> rumen acidosis and rumenitis
Treatment of Fusobacterium necrophorum in liver infection
Unrewarding but can control by preventing rumenitis- gradual increase in feed and disinfect naval at birth
Fusobacterium necrophorum In horses and cattle (not internal)
Thrush and foot rot
Diagnosed usually just by inspection of foot and treated with debriding, removing necrotic tissue and disinfecting then treating with antibiotics
Dichelobacter nodosus characteristics
aerotolerate gram negative anaerobic rod
Dichelobacter nodosus Pathogenic features
Pili is for adhesion
Dichelobacter nodosus Transmission
Resides on foot of carrier animals and is NOT inch GI tract
Can survive for a week in a warm wet pasture
Dichelobacter nodosus Disease
Foot rot in sheep and goats- contagious and debilitating with severe lameness which causes weight loss because reluctant to move. Usually occurs after Fusobacterium necrophorum has infected superficial skin and then D. nodosus colonizes after
How to diagnose, treat, and prevent Dichelobacter nodosus disease
Causes foot rot so inspecting usually to diagnose and then segregate infected animals, paring the feet and then foot baths to treat. There are herds that are foot rot free to get replacements from, but also quarantining new animals and not using contaminated pastures for 2 weeks