Salivary Glands Flashcards

1
Q

Salivary glands are___ glands & ___ cells

A

exocrine
secretory

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2
Q

what’s the order of development for the 3 major salivary glands?

A

Parotid anlagen are first to develop, then submandibular gland, & then sublingual gland

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3
Q

Parenchymal tissue (secretory) of the glands arises from the ___ in adults & ___ in developing fetus

A

proliferation of oral epithelium & ectoderm in the developing fetus

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4
Q

Stroma (capsule & septae) of the glands originates from

A

mesenchyme that may be mesodermal or neural crest in origin

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5
Q

Functions of the salivary glands

A

Protection
Buffering
Digestion
Antimicrobial
Antiviral
Antifungal
Maintenance of tooth integrity
Taste
Caries prevention
Temperature regulation

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6
Q

w/o saliva, you’re prone to

A

infections

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7
Q

What are the minor salivary glands? are they mucous, serous, or mixed?

A

Lingual
Anterior - mixed - mostly mucous
Posterior - mucous

Labial - mixed - mostly mucous

Buccal - mixed - mostly mucous

Palatine (hard & soft palate) - Mucous

Glossopalatine - mucous

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8
Q

What is the new salivary gland called? Where’s it located & is it a minor or major salivary gland?

A

Tubarial gland
Location is above the torus tubarius, the section of the nasopharynx just behind the pharynx
A minor salivary gland

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9
Q

Describe serous cells

A
  • produce a thin watery secretion
  • Also secrete polysaccharides
  • Stain purple
  • Has a rounded euchromatic nucleus surrounded by rough ER in the basal third of the cell
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10
Q

There’s an abundance of ___ in apical cytoplasm (NOT ribosomes or mitochondria)

A

zymogen granules

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11
Q

Where are serous cells found in the body?

A

Found in acinar cells of pancreas, parotid, gastric chief cells, & intestinal paneth cells

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12
Q

Describe mucous cells

A
  • produce a more viscous secretion
  • Production, storage, & secretion of proteinaceous material; smaller zygomatic component
  • More carbohydrates (attached to mucins)
  • More prominent golgi that adds carbohydrates to proteins
  • Less prominent rough ER & mitochondria
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13
Q

What are the major salivary glands?

A

Parotid, submandibular & sublingual

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14
Q

All salivary glands are ___ glands

A

compound tubuloalveolar

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15
Q

The salivary gland has intercalated, striated & ___ ducts & is composed of ___ acini & ___ cells

A

Secretory
Terminal
Myoepithelial

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16
Q

Parotid anlagen are first to develop, & become encapsulated before or after the submandibular

A

AFTER

17
Q

What happens before encapsulation of the parotid gland?

A

the lymphatic system develops - there are intraglandular lymph nodes & lymphatic channels that become entrapped within the parotid gland

18
Q

Describe the parotid gland. Provides ___ of total salivary volume. What’s its main duct in?

A
  • Largest encapsulated salivary gland
  • Pure serous
  • No serous demilunes (b/c only 1 cell type)
  • Provides 25% of total salivary volume
  • Main duct in Stenson’s duct
19
Q

What gland is this?

A

Parotid

20
Q

What gland is this?

A

Parotid

21
Q

Describe submandibular glans. It provides ___ of total salivary volume. What’s its main duct?

A
  • 2nd largest encapsulated salivary gland
  • Mixed - predominantly serous
  • Provides 60-65% of total salivary volume
  • Main duct is Wharton’s duct
22
Q

What salivary gland is this?

A

Submandibular

23
Q

What salivary gland is this?

A

Submandibular

24
Q

Describe the sublingual gland. It provides ___ of total salivary volume. What’s its main duct?

A
  • Smallest salivary gland
  • Unencapsulated gland
  • Mixed - predominantly mucous
  • Provides 10% of total salivary volume
  • Main duct is Bartholin’s duct
25
Q

What salivary gland is this?

A

Sublingual

26
Q

What salivary gland is this? What else can you see in this image?

A

Sublingual

Blood capillaries (RBC)

27
Q

Intercalated ducts are lined by ___. Where do they develop?

A

simple squamous to low cuboidal epithelial cells rich in carbonic anhydrase

mucous glands

28
Q

Striated glands are ___ in mucous glands

A

nonexistent

29
Q

In striated glands, cells absorb ___ from the lumen & secrete ___ into the luen

A

Na+ & K+

30
Q

Striated ducts are ___ cells

A

simple cuboidal epithelial cells

31
Q

Excretory ducts are lined by

A

simple columnar epithelium proximally & stratified cuboidal (2 layers) or pseudostratified columnar epithelium distally

32
Q

Location & function of myoepithelial cells

A
  • Found between the acinar cells & basal lamina
  • Function: contraction when gland is secreting & aid in the expulsion of saliva
33
Q

Effects of aging in relation to the salivary gland

A
  • Acinar cells degenerate w/ age
  • Submandibular gland more sensitive to metabolic/physiologic change
34
Q

Salivary hypofunction examples

A

Candidiasis
Lichen planus
Burning mouth
Aphthous ulcers
Dental caries
Xerostomia

35
Q

Less saliva production is connected to

A

dry eyes

36
Q

What is xerostomia?

A

Dry mouth
- often due to medications or radiation

37
Q

Label

A
  1. Basal lamina
  2. Myoepithelial cells
  3. Acinar cells
  4. Acinus
  5. Intercalated duct
  6. Striated duct