Salivary Glands Flashcards
Salivary glands are___ glands & ___ cells
exocrine
secretory
what’s the order of development for the 3 major salivary glands?
Parotid anlagen are first to develop, then submandibular gland, & then sublingual gland
Parenchymal tissue (secretory) of the glands arises from the ___ in adults & ___ in developing fetus
proliferation of oral epithelium & ectoderm in the developing fetus
Stroma (capsule & septae) of the glands originates from
mesenchyme that may be mesodermal or neural crest in origin
Functions of the salivary glands
Protection
Buffering
Digestion
Antimicrobial
Antiviral
Antifungal
Maintenance of tooth integrity
Taste
Caries prevention
Temperature regulation
w/o saliva, you’re prone to
infections
What are the minor salivary glands? are they mucous, serous, or mixed?
Lingual
Anterior - mixed - mostly mucous
Posterior - mucous
Labial - mixed - mostly mucous
Buccal - mixed - mostly mucous
Palatine (hard & soft palate) - Mucous
Glossopalatine - mucous
What is the new salivary gland called? Where’s it located & is it a minor or major salivary gland?
Tubarial gland
Location is above the torus tubarius, the section of the nasopharynx just behind the pharynx
A minor salivary gland
Describe serous cells
- produce a thin watery secretion
- Also secrete polysaccharides
- Stain purple
- Has a rounded euchromatic nucleus surrounded by rough ER in the basal third of the cell
There’s an abundance of ___ in apical cytoplasm (NOT ribosomes or mitochondria)
zymogen granules
Where are serous cells found in the body?
Found in acinar cells of pancreas, parotid, gastric chief cells, & intestinal paneth cells
Describe mucous cells
- produce a more viscous secretion
- Production, storage, & secretion of proteinaceous material; smaller zygomatic component
- More carbohydrates (attached to mucins)
- More prominent golgi that adds carbohydrates to proteins
- Less prominent rough ER & mitochondria
What are the major salivary glands?
Parotid, submandibular & sublingual
All salivary glands are ___ glands
compound tubuloalveolar
The salivary gland has intercalated, striated & ___ ducts & is composed of ___ acini & ___ cells
Secretory
Terminal
Myoepithelial
Parotid anlagen are first to develop, & become encapsulated before or after the submandibular
AFTER
What happens before encapsulation of the parotid gland?
the lymphatic system develops - there are intraglandular lymph nodes & lymphatic channels that become entrapped within the parotid gland
Describe the parotid gland. Provides ___ of total salivary volume. What’s its main duct in?
- Largest encapsulated salivary gland
- Pure serous
- No serous demilunes (b/c only 1 cell type)
- Provides 25% of total salivary volume
- Main duct in Stenson’s duct
What gland is this?
Parotid
What gland is this?
Parotid
Describe submandibular glans. It provides ___ of total salivary volume. What’s its main duct?
- 2nd largest encapsulated salivary gland
- Mixed - predominantly serous
- Provides 60-65% of total salivary volume
- Main duct is Wharton’s duct
What salivary gland is this?
Submandibular
What salivary gland is this?
Submandibular
Describe the sublingual gland. It provides ___ of total salivary volume. What’s its main duct?
- Smallest salivary gland
- Unencapsulated gland
- Mixed - predominantly mucous
- Provides 10% of total salivary volume
- Main duct is Bartholin’s duct
What salivary gland is this?
Sublingual
What salivary gland is this? What else can you see in this image?
Sublingual
Blood capillaries (RBC)
Intercalated ducts are lined by ___. Where do they develop?
simple squamous to low cuboidal epithelial cells rich in carbonic anhydrase
mucous glands
Striated glands are ___ in mucous glands
nonexistent
In striated glands, cells absorb ___ from the lumen & secrete ___ into the luen
Na+ & K+
Striated ducts are ___ cells
simple cuboidal epithelial cells
Excretory ducts are lined by
simple columnar epithelium proximally & stratified cuboidal (2 layers) or pseudostratified columnar epithelium distally
Location & function of myoepithelial cells
- Found between the acinar cells & basal lamina
- Function: contraction when gland is secreting & aid in the expulsion of saliva
Effects of aging in relation to the salivary gland
- Acinar cells degenerate w/ age
- Submandibular gland more sensitive to metabolic/physiologic change
Salivary hypofunction examples
Candidiasis
Lichen planus
Burning mouth
Aphthous ulcers
Dental caries
Xerostomia
Less saliva production is connected to
dry eyes
What is xerostomia?
Dry mouth
- often due to medications or radiation
Label
- Basal lamina
- Myoepithelial cells
- Acinar cells
- Acinus
- Intercalated duct
- Striated duct