S. Aureus - S.capitus Flashcards

1
Q

S. Aureus is gram (__), faculative ____, and is shaped like ____

A

+; coccus; grapes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

S. Aureus is catalase __ and coagulase ___

A

+; +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

S. Aureus is the 2nd leading nosocomial infection. True or false?

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

S. aureus can be resistant to ___ and ___ and also cause _____

A

ph; heat/cold; desiccation (dryness)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
In order to ID s. aureus, what do you need to do for the following:
abcess
bacteremia
SSS
bullous impetigo
TSS
food poisoning
A

abcess: scrape and do a gram stain
bacteremia: culture blood
SSS: culture nasopharyngeal samples
bullous impetigo: culture blister fluid
TSS: vaginal secretions have cocci, blood (-)
food poisoning: check food, not poop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What color does S. Aureus grow on a manitol-salt agar plate?

A

yellow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What color does S. Aureus grow on tellurite-glycine agar plate?

A

black

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In regards to color and hemolysis, what do S. Aureus colonies look like on blood agar plate?

A

hemolytic yellow colonies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

S. Aureus is typically found in the ___

A

nares

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is USA300?

A

MRSA in US

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

In regards to diseases causes by S. Aureus, who is at risk for SSS and TSS

A

SSS: newborns, kids with bad hygiene
TSS: women (from catheters)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

S. Aureus is the #1 cause of this disease. It presents as macule and becomes a pustule with a honey brown crusting. It is acute and contagious.

A

Impetigo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

S. Aureus is the #1 cause of this disease. It is superficial, pyogenic infection of a hair follicle, and a result of poor hygiene.

A

Folliculitis and Furuncle (if several)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

This disease caused by s. aureus is similar but more serious than Folliculitis/Furuncle. The boils are located on the back of the neck, back, and buttocks and the patient may also have signs of septicemia (chills, fever).

A

carbuncle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does S. aureus present in a wound infection?

A

edema, redness, pain, purulent fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In regards to wound infections, S. Aureus can cause Mastitis, bacteremia, and endocarditis. Describe each situation.

A

mastitis: ductal system, creaked nipples, tenderness, fatigue
bacteremia: after surgery of contaminated IV/Cath
endocarditis: life threatening, increased freq. of embolization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

This disease in the lungs is caused by S. Aureus is mostly nosocomial. It is serious in those who are already ill and may be due to aspiration of oral secretions. P-V leukocidins may be a big cause of this disease in the community. Toxins involved can cause tissue destruction, massive hemoptysis, and septic shock.

A

pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

S. aureus is the most common cause of the acute form of this disease. In this disease there is a hematogenous spread or extension from a S/C infection. In kids it occurs in metaphyseal areas of long bones and in adults it occurs in vertebra (rare in long bones). There is a sudden onset of localized pain and fever associated.

A

osteomyelitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

S. Aureus is the most common cause of this disease, except those who are sexually active. With this disease, there is painful movement, red swollen joints, pus in aspirated joint fluid, and occurs commonly in the knee.

A

septic arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

This disease caused by S. aureus is associated with an abrupt onset of perioral erythema and covers the entire body in 24 hours. There are large blisters with fluid but no organism. Deescalation also occurs. The nikolsky’s sign is positive for this disease (pressure displaces skin).

A

Scalded skin syndrome (Ritter’s disease)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

This disease caused by s. aureus is a localized form of SSSS. The erythema does not extend beyond the borders of blisters and unlike SSSS, organism is in the blister fluid

A

bullous impetigo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

This disease caused by S. aureus is associated with an abrupt onset of fever, erythematous rash over the entire skin. The palms and soles desquamate. Patients also have a marked red tongue. More than 90% of the cases of this disease are in menstruating women. The pathology of this disease is associated with massive release of cytokines.

A

TSS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

S. aureus is the most common cause of this disease. It produces 8 distinct enterotoxins that are heat stable. There is severe vomiting associated with this disease. In the vomit, there is only toxin.

A

staphylococcal food poisoning

note: toxin impacts CNS

24
Q

S. aureus is the #2 cause of this disease which causes watery diarrhea, abdominal cramps. The mucous in the stool has bacteria. Strains of s. aureus causing this disease make enterotoxin A and leukotoxin

A

antibiotic associated enterocolitis

25
Q

In regards to virulence, what is the purpose of s. aureus’ capsule?

A

inhibits chemotaxis and phagocytosis, allows adherence to foreign bodies

26
Q

In regards to virulence, what is the purpose of s. aureus’ PG?

A

inhibits phagocytosis, endotoxin-like acitivity

27
Q

In regards to virulence, what is the purpose of s. aureus’ teichoic acid

A

regulates cationic concentration at cell membrane, binds Fn.

28
Q

In regards to virulence, what is the purpose of s. aureus’ protein A?

A

binds IgG, inhibits opsonization, complement activation

29
Q

In regards to virulence, what is the purpose of s. aureus’ coagulase enzyme?

A

converts FB to fibrin = clot

30
Q

In regards to virulence, what is the purpose of s. aureus’ catalase enzyme?

A

removes hydrogen peroxide

31
Q

In regards to virulence, what is the purpose of s. aureus’ hyalurinidase enzyme?

A

spreading factor

32
Q

In regards to virulence, what is the purpose of s. aureus’ nucleases?

A

pus -> spreading factor

33
Q

In regards to virulence, what is the purpose of s. aureus’ lipases?

A

allows colonization of skin

34
Q

In regards to virulence, what is the purpose of s. aureus’ ETA/ETB serine proteases?

A

digest anchors holding epidermis to dermis

35
Q

In regards to virulence, what is the purpose of s. aureus’ alpha, beta, and gamma leukocidins?

A

toxic for WBCs, RBCs, platelets, macrophages, and fibroblasts

36
Q

In regards to virulence, what is the purpose of s. aureus’ enterotoxins (A-R) and TSST-1?

A

superantigens (act on T-cells/MHC class II, releases TNF-alpha and IL 1 and 2)

37
Q

S. epidermidis is gram (__) and is in purple ____

A

+; clusters

38
Q

S. epidermidis is catalase ___ and coagulase ___

A

+ ; -

39
Q

What do S. epidermidis colonies look like on blood agar plate, in regards to hemolysis and color?

A

white, non-hemolytic colonies

40
Q

What does S. epidermidis look like on a MSA plate?

A

doesn’t ferment - purple

41
Q

What does S. epidermidis look like on a tellurite plate?

A

doesn’t ferment - white

42
Q

S. epidermidis and S. saprophyticus are ___ resistant (antibiotic)

A

novobiocin

43
Q

S. epidermidis is found in ___ and on ___

A

nares; skin

note: may also be in URT, GIT, UGT

44
Q

S. epidermidis is highly nosocomial and has a carriage rate of ___

A

100%

45
Q

Disease caused by S. epidermidis is highly associated with ____ ____

A

intravascular devices (prosthetic heart valves, artificial joints, shunts)

46
Q

S. epidermidis can also cause ____- induced UTIs and bacteremias

A

catheter

47
Q

With this disease, caused by s. epidermidis, there is sepsis, embolizaiton, CHF, cardiac rupture, and a 60% mortality rate.

A

prosthetic valve endocarditis

48
Q

S. epidermidis lacks protein ___, ___-toxin, and coagulase

A

A; alpha

49
Q

S. epidermidis is hardly ever drug resistant. True or false?

A

false; often drug resistant

50
Q

What is the main source of virulence in s. epidermidis?

A

slime - biofilm that allows adherence to catheters and interferes with phagocytosis

51
Q

S. saprophyticus is catalase __ and coagulase __

A

+ ; _

52
Q

What does S. saprophyticus look like on a blood agar plate, in regards to hemolysis and color?

A

white, non-hemolytic colonies

53
Q

What does S. saprophyticus look like on a MSA plate?

A

doesn’t ferment - purple

54
Q

Where is S. saprophyticus infection usually found?

A

skin and UGT mucosa; endogenous spread to UT in women

55
Q

This S. saprophyticus disease is the 2nd most common cause of UTI in sexually active women.

A

cystitis

note: cystitis, peylonephritis; dysuria, pyruria are common and frequently drug resistant

56
Q

S. haemolyticus and s. captious are both found in normal skin flora in axilla and perineum. What disease do they cause?

A

endocarditis, UTI, wound infections, opportunistic infections