Routes of Administration Flashcards

1
Q

Benefits of tablets

A

convenient, accurate dosage.

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2
Q

Negatives of tablets

A

can’t be bitten, fluid needed alongside

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3
Q

Routes for capsules

A

sublingual and buccal

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4
Q

Difficulty with capsules

A

large, hard to swallow

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5
Q

Liquids must be

A

shaken well before use and mixed.

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6
Q

Peripheral Cannula is inserted

A

into peripheral vein in arms and legs

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7
Q

Central venous catheter

A

placed into large vein in neck, chest, groin.

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8
Q

Implanted port catheter known as

A

port-a-cath

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9
Q

Tunnelled catheter called a

A

Hickman line

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10
Q

For fluid replacement which IV fluid is used

A

Isotonic saline

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11
Q

Synthetic Colloids are used to

A

expand volume

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12
Q

Glucose and glucose salines provide

A

free water

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13
Q

Balanced crystalloid solution

A

improves replacement

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14
Q

Complications with IV therapy

A

infection, Phlebitis and tissue infiltration.

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15
Q

Intravenous fluid therapy used to

A

maintain and restore fluid and electrolyte balance

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16
Q

Intramuscular injections can be given where

A

deltoid, dorsogluteal and ventrogluteal

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17
Q

Powders require

A

re-constitution in a solution

18
Q

Intradermal injection are done on the

A

inner lower arm with small amount of fluid

19
Q

Subcutaneous injections are

A

just beneath the skin, site of injection rotated

20
Q

Parental routes

A

intramuscular, intravenous, intradermal, subcutaneous, intrathecal, epidural

21
Q

Rectal route benefits

A

local or systemic, useful for vomiting patients.

22
Q

Rectal route disadvantages

A

training needed, unpopular, not always suitable.

23
Q

Transdermal benefits

A

long lasting, convenient, suitable for most

24
Q

Transdermal disadvantages

A

absorption varies, adverse skin effects, must be lipid soluble and very potent

25
Inhilation benefits
local or systemic effect, rapid
26
Inhilation disadvantages
difficulty in reaching site of action
27
Topical administration benefits
convenient, minimal risk of overdose
28
Topical administration negatives
adverse skin effects
29
Bioavailability is
% of drug that makes it into drug stream
30
Oral administration benefits
well absorbed, convenient
31
Oral administration negatives
variable absorption, not appropriate for everyone, depends on stomach content.
32
Drug potency
more potent in smaller people, 1st time drug user, usual drug user.
33
Formulations of medicines
capsule, tablet, creams, powders, gels, solutions, syrups, gases, sprays, aerosols, lotions, implants.
34
Organ with greatest blood flow
Kidney
35
Water soluble drugs require
injections
36
Distribution is the
transfer of absorbed drug into and out of various tissues in the body from the bloodstream
37
Distribution affected by
lipid solubility of drug, blood flow and binding of drugs to proteins
38
Metabolism is the enzyme mediated conversion of
a lipid soluble compound into a more water soluble one
39
For excretion of drugs they must be metabolised and
converted to water soluble drug.
40
Free drugs can bind to proteins in the
plasma
41
What drugs diffuse across membranes to have an effect
free drugs