Dosage regimens

Question 1

Half life is

Answer 1

time taken for amount of drug in body to decrease by half of maximum level

Question 2

Half life is important is it lets us know

Answer 2

toxic concentration levels in body and when to stop 1 drug and start another

Question 3

If patients have renal or hepatic disease what will happen to the half life

Answer 3

increase

Question 4

To excrete a drug there is an increased blood flow to

Answer 4

the kidneys and a decreased level of plasma protein binding

Question 5

Drug metabolising enzymes can be

Answer 5

inhibited (Prozac) and induced (Alcohol)

Question 6

Pharmacological activation is

Answer 6

when products are more reactive than the parent drug

Question 7

Phase 1 reactions prepare drugs for phase 2 and

Answer 7

make drugs more water soluble

Question 8

Phase 2 reactions conjugate drug to

Answer 8

create large molecules like amino acids.

Question 9

Pharmacological inactivation is

Answer 9

when drugs are inactive with decreased affinity for receptors