Diuretics Flashcards
Diuretics increase
amount of fluid and salts excreted by kidney, urine production increases
Diuretics act at
different sites
Thiazide acts at
distal convulated tubule
Loop diuretics act at
ascending loop of henle
Potassium sparing diuretics act at
late distal tubule and collecting duct
Anti diuretics act
on collecting tubule
Examples of antidiuretics
vasopressin, desmopressin
Desmopressin + and -‘s
nasal spray, longer duration, no BP affect, dosage must be balanced.
Potassium sparing diuretics like Spironolactone and Amiloride are used to treat
hypotension and oedema
Potassium sparing diuretics increase excretion of
chlorine and calcium and sodium and water.
Loop diuretics metabolised by
liver
Loop diuretics block increase excretion of
sodium, potassium and chlorine
Thiazide diuretics block which pump
chlorine pump on apical membrane, sodium, potassium and chloride excreted
