ROLES OF OESTROGEN Flashcards

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1
Q

WHAT HORMONES REGULATE OVARIAN AND UTERINE CYCLES

A

GONATROPHIN RELEASING HORMONE
GONADATROPHINS - FOLLICLE STIMULATING HORMONE AND LUTENISING HORMONE
OESTROGEN
PROGESTERONE

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2
Q

WHAT PROMPTS THE RELASE OF FSH AND LH FROM THE ANT PITUITARY

A

GONADATROPHIN RELEASING HORMONE

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3
Q

WHAT IS THE FUNCTION OF FOLLICLE STIMULATING HORMONE

A

STIMULATES OVARIAN FOLLICLE MATURATION
OVARIAN PRODUCTION OF OESTROGEN

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4
Q

WHAT IS THE FUNCTION OF LUTENISING HORMONE

A

TRIGGERS OVULATION AND FORMATION OF CORPUS LUTEUM
OVARIAN PRODUCTION OF PROGESTERONE AND OESTROGEN

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5
Q

ARE THE FEMALE SEX HORMONES AMINO ACID OR STEROID HORMONES

A

STERIOD

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6
Q

DESCRIBE THE HYPOTHALAMIC-PITUATARY-GONADAL ACCESS

A

THE HYPOTHALAMUS RELEASED GONADATROPHIN RELEASING HORMONE
WHICH TELLS THE ANTERIOR PITUATARY GLAND TO RELEASE FSH AND LH
BOTH TRAVEL TO THE OVARIES AND INTERACT WITH THE GRANULOSA AND THECAL CELLS TO PRODUCE PROGESTERONE AND OESTROGEN

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7
Q

WHAT ARE THE FUNCTIONS OF OESTROGENS

A

PROMOTE OOGENSIS
MAINTAIN THE REPRODUCTIVE TRACT
CV PROTECTIVE ROLE AS A BLOOD VESSEL DIALATOR
MAINTAIN BONE DENSITY

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8
Q

WHAT PRODUCES PROGESTERONE

A

THE CORPUS LUTEUM

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9
Q

WHAT IS THE FUNCTION OF PROGESTERONE

A

PREPARES THE ENDOMETRIUM FOR IMPLANTATION
FORMS THE CERVICAL MUCOUS PLUG IN PREGNANCY

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10
Q

WHAT CELLS FORM ANDROGENS

A

THECAL CELLS

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11
Q

WHAT CELL CONVERTS ANDROGENS TO OESTROGENS

A

GRANULOSA CELLS

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12
Q

WHAT ENZYME IS REQUIRED FOR THE CONVERSION OF ANDROGENS TO OESTROGEN

A

AROMATASE

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13
Q

DO BOTH THECAL AND GRANULOSA CELLS PRODUCE PROGESTERONE

A

YES

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14
Q

FSH BINDS TO WHICH CELL

A

GRANULOSA CELL

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15
Q

LH BINDS TO WHICH CELLS

A

THECAL AND GRANULOSA

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16
Q

DESCRIBE THE SYNTHESIS OF OESTROGEN REGARDING THE GRANULOSA AND THECAL CELLS

A

WITHIN BOTH CELLS CHOLESTEROL IS CONVERTED INTO PROGESTERONE.
THE GRANULOSA CELLS CANNOT CONVERT PROGESTERONE INTO ANDROGENS SO THEY SEND THEIR PROGESTERONE TO THE THECAL CELLS WHERE ANDROGENS ARE CREATED. THE THECAL CELLS THEN SEND THE ANDROGENS TO THE GRANULOSA CELLS WHERE AROMATASE HELPS TO CONVERT ANDROGENS TO OESTROGENS