RNA to protein Flashcards

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1
Q

What are 5 characteristics of the codon?

A
  1. 3 bases= one codon= one amino acid
  2. The code is non overlapping
  3. Degenerate code
  4. Start codon= Aug= Met
  5. Stop codon- UAA, UAG, UGA
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2
Q

How is wobble base pairing achieved?

A

Deamination of adenine to create an inosine

Inosine can pair to U,C or A

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3
Q

What happens to an amino acid before it forms an aminoacyl-tRNA

A

A synthetase primes the amino acid by adding AMP to the C terminus

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4
Q

What does peptidyl transferase do?

A

Catalyses the amino acid addition to the growing protein strand

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5
Q

What does EF1 do?

A

Causes a delay before the peptidyl transferase can act

  1. GTP hydrolysed to GDP
  2. EF1 dissociates from the tRNA
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6
Q

What happens at the start of translation?

A

tRNA carrying Met with EIF2 binds to small subunit

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7
Q

What binds to mRNA that still has a cap and a tail?

A

EIF-4G and EIF-4E

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8
Q

Structural components of HS60?

A

Hydrophobic entrance

GroES cap

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9
Q

What are amyloid plaques seen in?

A

Alzheimers- cross beta filaments

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