Mitosis and meiosis Flashcards
1
Q
What are the stages of the cell cycle called?
A
G1
S
G2
M
2
Q
What are the stages of M phase?
A
Prophase Prometaphase Metaphase Anaphase Telophase
3
Q
What are the checkpoints in the cell cycle?
A
1.G1->S Is the environment favourable? 2.G2->M Is the environment favourable? Is all the DNA replicated? 3.Metaphase->Anaphase Are all the chromosomes lined up at the spindle?
4
Q
Examples of proteins that modify Cdk activity
A
Cyclins
P27 (inhibitory)
Wee1 kinase (inhibitory)
Cdc25 phosphatase (activation)
5
Q
What happens in meiosis 1?
A
Crossing over an segregation
6
Q
What happens in meiosis 2?
A
Segregation of the sister chromatids- 4 daughter cells produced
7
Q
3 tools to detect proliferation
A
Dapi- DNA dye
Fluorescent antibodies- detect BrDU
Pulse-treatment- see which cells were in S phase when treated
