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Structure And Function III > Richardson - Lymphoid Tissue > Flashcards

Richardson - Lymphoid Tissue Flashcards

1
Q

Function of lymphoid tissues

A

Protect body from foreign substances and organisms

Distinguish self from non-self

Remove infected, damaged, or cancerous cells

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2
Q

Molecules that bind to antibodies or the T cell receptors

(Antibodies bind small regions of large molecules)

(T cell receptors bind small peptides processed from larger proteins)

A

Antigen

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3
Q

The N terminal region of heavy and light chains in antibodies is ____

A

Highly variable

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4
Q

Membrane bound antibodies have a _______ domain at the C terminal

A

Transmembrane

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5
Q

Form: membrane and secreted pentamer

Function: B cell antigen receptor

A

IgM

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6
Q

Form: membrane

Function: B cell antigen receptor:

A

IgD

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7
Q

Form: secreted, major immunoglobulin found in serum

Function: phagocytosis, Neonatal immunity

A

IgG

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8
Q

Form: secreted, binds to receptors on mast cells

Function: allergic reactions, parasites

A

IgE

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9
Q

Form: secreted Dimer

Function: mucosal immunity

A

IgA

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10
Q

Membrane bound antibodies
• Recognize epitopes on a variety of
extracellular macromolecules

A

B lymphocytes

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11
Q

• T cell receptor (TCR)
• Recognizes small peptides on the surface
of antigen presenting cells or infected cells

A

T Lymphocytes

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12
Q

Initial recognition and processing of antigens, done by dendritic cells, macrophages, and neutrophils

A

Innate immunity

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13
Q

Immune response and effector function

Lymphocytes
b cells - humoral
T cells- cell mediated

Plasma cells

A

Adaptive immunity

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14
Q

Part of adaptive immunity

Function to produce large quantities of antibodies

A

Plasma cells

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15
Q

Part of adaptive immunity.

Recoginzes antigens inside cells that are presented to the TCR

A

T Cells - cell mediated immunity

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16
Q

Part of adaptive immunity

Recognizes antigens outside the cell

A

B cells - humoral immunity

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17
Q

Neutrophils, macrophages, and langerhans cells are all part of the -_____- immmune system

A

Innate

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18
Q

Immature T cells migrate to _____ for further maturation

A

Thymus

19
Q

Where does the negative selection for T cells that recognize self too strongly occur? (This prevents autoimmune disease)

A

Thymus

20
Q

Filter for the lymph

A

Lymph nodes

21
Q

Filter for the blood

Removal of aged red blood cells

A

Spleen

22
Q 
• Located throughout the
body along lymph
vessels • Filter for the lymph
• Monitors for foreign
antigens in tissues • Adaptive immune
responses to lymph-
borne antigens initiated
A

Lymph nodes

23
Q

Lymphocytes enter lymph nodes from blood through

A

High endothelial venules (HEV)

24
Q

Lymphocytes leave lymph nodes via

A

Efferent lymphatic vessels

25
Q

Lymphocytes enter blood circulation through

A

Lymphatic ducts

26
Q

High endothelial venules are found in secondary lymphoid tissues except___

A

Spleen

27
Q

Where is mucosa -associated Lymphoid tissue (MALT) found?

A

In lamina propria underlying the mucosal epithelium of tissues w openings to external environment

GI tract
Respiratory tract
Reproductive tract

28
Q

The T cell receptors bind ____

A

Small peptides processed from larger proteins

29
Q

Immunoglobulin isotypes that are found in membranes

A

IgM

IgD

30
Q

Pentamer immunoglobulin isotype

A

IgM

31
Q

Major functions for lymph nodes

A

Filter lymph

Phagocytosis of bacteria / foreign substances from lymph

32
Q

After entering the lymph nodes, B cells congregate on _______ of lymph nodes’ outer cortex

A

Lymphatic nodules

33
Q

T cells congregate _____ the lymphatic nodules in the deep cortical or paracortical regions

A

Below

34
Q

Lymph nodes are the location of _____ and _____ of B cells which gives rise to plasma cells and memory B cells

A

Antigenic recognition and antigenic activation

35
Q

Circulating lymphocytes recognize __________ on high endothelial cells to know to enter lymph nodes from the blood

A

Lymphocyte homing receptors

36
Q

In spleen; white pulp contains ?

A

B and T lymphocytes

37
Q

In spleen; red pulp contains __

A

RBC’s, macrophages, and other blood cells

38
Q

Ciliated pseudostratified columnar
epithelium, but can also have stratified squamous epithelium
• No crypts

A

Pharyngeal tonsil

39
Q

Lateral walls of the oral pharynx
• Stratified squamous epithelium
• Multiple crypts

A

Palatine tonsil

40
Q

Large amounts of ____ are secreted by plasma cells and subsequently transported across the epithelium into the lumen of the tissue in Mucosa-associated lymphoid tissue (MALT), which is found in lamina propria

A

IgA

41
Q

Antibodies bind __

A

Small regions of large molecules

42
Q

Immunoglobulin isotype that binds to mast cells to release histamine

A

IgE

43
Q

Main function of thymus gland

A

Produce a diverse group of T cells that can respond to antigens

Structure And Function III (24 decks)

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