Kim- Microcirculation

Question 1

have a very .ght endothelium and con.nuous
basement membrane, which reduces bulk flow across the capillary wall.
»  skeletal muscle, skin, lung, and brain

Answer 1

Continuous capillaries

Question 2

have perfora.ons (fenestrae) in the
endothelium, resul.ng in rela.vely high permeability and bulk flow.
»  exocrine glands, renal glomeruli, and intes.nal mucosa

Answer 2

Fenestrated capillaries

Question 3

have large intercellular gaps, as well as gaps
in the basement membrane, resul.ng in the highest permeability.
»  liver, spleen, and bone marrow

Answer 3

Discontinuous capillaries

Question 4

Plays relatively minor role in transcapillary exchanges.

May be used to transport macromolecules (Proteins)

Answer 4

Vesicular transport

Question 5

The rate of oxygen diffusion across capillaries can be enhanced by;

Answer 5

Increasing capillary blood pO2 (inhale pure O2, dilate of resistance vessels)

Decreasing tissue pO2 (increased consumption)

Increase vessel surface area available for diffusion (an increase in the number of flowing capillaries happens in skeletal muscle contraction)

Question 6

Carbon dioxide diffusion from cells into the blood happens readily. In aqueous solution, carbon dioxide diffusions constant is about ____ times greater than oxygen

Answer 6

20

Question 7

Fluid movement due to osmotic pressure is usually in the direction of ?

Answer 7

Interstitium TO capillary

Question 8

Main protein determining protein concentration in the capillaries?

Answer 8

Albumin (about 70%)

Question 9

Causes of edema:

Answer 9

Increased capillary pressure

Increased papillary permeability (vascular damage)

Decreased plasma oncotic pressure

Lymphatic blockage (lymphedema)