Rhinosinusitis - epistaxis - DVT/PE Flashcards
epistaxis
nose bleeding
epistaxis - MC occurs in (area)
anterior segment of nostril (KIESSELBACH PLEXUS)
epistaxis - life threatening
life threatening haemorrhages occurs in posterior segment of nostril (sphenopalatine artery, a branch of maxillary artery)
posterior segment of nostril epistaxis
life threatening hemorrhages (sphenopalatine artery, a branch of maxillary artery)
Rhinosinusitis pathophysiology
obstruction of sinus drainage into nasal cavity –> inflammation and pain over affected area
Rhinosinusitis symptoms
- pain over affected area
2. Maybe loss of smell
MC acute cause of Rhinosinusitis
viral URI
Rhinosinusitis MAY CAUSE
superimposed bacterial infection, most commonly by
a. S. pneumonia
b. H. influenza
c. M catarrhalis
Typical area for Rhinosinusitis
maxillary sinuses, which drain into middle meatus, in adults
Rhinosinusitis - what may show in CT
nasal septal deviation
deep venous thrombosis - definition
blood clot within a deep vein
deep venous thrombosis - symptoms
- swelling
- redness
- warmth
- pain
deep venous thrombosis is predisposed by
Virchow triad
- stasis
- hypercoagulability
- Endothelial damage
virchow triad - endothelial damage
exposed collagen triggers clotting cascade
virchow triad - hypercoagulability
defect in coagulation cascade proteins, such as factor V Leiden
Homan sign
DVT
dorsiflexion of foot –> calf pain
most of pulmonary emboli arise from ….
proportion?
proximal deep veins of lower extremity
95%
prophylaxis and acute management of DVT
unfractionated heparin
OR
low molecular weight heparin
treatment (long time prevention) of DVT
oral anticoagulants (e.g. warfarin, rivaroxaban)
imaging study for pulmonary emboli
look for
CT pulmonary angiography
look for filling defects
Pulmonary emboli - CT pulmonary angiography
look for
filling defects
types/causes of pulmonary emboli
mnemomic: FAT BAT
1. Fat 2. Air 3. Thrombus 4. Bacteria 5. Amnionionic fluid 6. Tumor
pulmonary emboli symptoms
- sudden onset of dyspnea
- chest pain
- tachypnea
- tachycardia
- SUDDEN DEATH
air emboli pathophysiology
nitrogen bubbles precipitate in ascending divers (caison disease, decompression sickness)
air emboli treatment
hyperbaric O2
fat emboli - situations
- long bone fractures
2. liposuction
fat emboli - symptoms
classic triad:
- hypoxemia
- neurologic abnormalities
- petechial rash
thrombi pulmonary emboli - histology
lines of Zahn: interdigitating areas of pink (platelets, fibrin) and red (RBCs) found only in thrombi formed before death
lines of Zahn: pink areas
platelets and fibrin
lines of Zahn: red areas
RBCs
lines of Zahn - utility
help distinguish pre and postmortem thrombi
Pulmonary embolism - ph (mechanism)
V/Q mismatch –> hypoxemia –> respir alkalosis
Amnionic fluid emboli can lead to (according to Lungs)
DIC, especially postpartum
tumor that causes DVT
glucagonoma
glucagonoma symptoms
- dermatitis (necrolytic migratory erythema)
- diabetes (hyperglycemia)
- DVT
- Depression
Head and neck cancer - type
mostly SCC
Head and neck cancer - risk factors
- tobacco
- alcohol
- HPV-16 (oropharyngeal)
- EBV (nasopharyngeal
Head and neck cancer - HPV-16 vs EBV
HPV-16 –> oropharyngeal
EBV –> nasopharyngeal
Head and neck cancer - filed cancerization
carcinogens gamage wide mucosal area –> multiple tumors